Boundary-aware Semi-supervised Deep Learning for Breast Ultrasound Computer-Aided Diagnosis

Erlei Zhang, Stephen Seiler, Mingli Chen, Weiguo Lu, Xuejun Gu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Breast ultrasound (US) is an effective imaging modality for breast cancer diagnosis. US computer-aided diagnosis (CAD) systems have been developed for decades and have employed either conventional handcrafted features or modern automatic deep-learned features, the former relying on clinical experience and the latter demanding large datasets. In this paper, we developed a novel BASDL method that integrates clinical-approved breast lesion boundary characteristics (features) into a semi-supervised deep learning (SDL) to achieve accurate diagnosis with a small training dataset. Original breast US images are converted to boundary-oriented feature maps (BFMs) using a distance-transformation coupled with a Gaussian filter. Then, the converted BFMs are used as the input of SDL network, which is characterized as lesion classification guided unsupervised image reconstruction based on stacked convolutional auto-encode (SCAE). We compared the performance of BASDL with conventional SCAE method and SDL method that used the original images as inputs, as well as SCAE method that used BFMs as inputs. Experimental results on two breast US datasets show that BASDL ranked the best among the four networks, with classification accuracy around 92.00±2.38%, which indicated that BASDL could be promising for effective breast US lesion CAD using small datasets.

Original languageEnglish (US)
Title of host publication2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages947-950
Number of pages4
ISBN (Electronic)9781538613115
DOIs
StatePublished - Jul 2019
Event41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019 - Berlin, Germany
Duration: Jul 23 2019Jul 27 2019

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)1557-170X

Conference

Conference41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019
CountryGermany
CityBerlin
Period7/23/197/27/19

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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    Zhang, E., Seiler, S., Chen, M., Lu, W., & Gu, X. (2019). Boundary-aware Semi-supervised Deep Learning for Breast Ultrasound Computer-Aided Diagnosis. In 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019 (pp. 947-950). [8856539] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2019.8856539