Brain repair by endogenous progenitors

Genevieve M. Kruger; Sean J. Morrison

doi:10.1016/S0092-8674(02)00899-1

Brain repair by endogenous progenitors

Genevieve M. Kruger, Sean J. Morrison

Research output: Contribution to journal › Review article › peer-review

66 Scopus citations

Abstract

Stem cells within the adult brain can be stimulated by injury and growth factor treatment to replace damaged neurons, even neurons that are not normally generated in adults. Coupled with recent insights into the mechanism by which Nogo inhibits axonal regeneration, this discovery may inspire new treatments for central nervous system injuries and neurodegenerative diseases.

Original language	English (US)
Pages (from-to)	399-402
Number of pages	4
Journal	Cell
Volume	110
Issue number	4
DOIs	https://doi.org/10.1016/S0092-8674(02)00899-1
State	Published - Aug 23 2002

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1016/S0092-8674(02)00899-1

Cite this

@article{dc1334f81edf4f65a8e1996ae456d4d2,

title = "Brain repair by endogenous progenitors",

abstract = "Stem cells within the adult brain can be stimulated by injury and growth factor treatment to replace damaged neurons, even neurons that are not normally generated in adults. Coupled with recent insights into the mechanism by which Nogo inhibits axonal regeneration, this discovery may inspire new treatments for central nervous system injuries and neurodegenerative diseases.",

author = "Kruger, {Genevieve M.} and Morrison, {Sean J.}",

year = "2002",

month = aug,

day = "23",

doi = "10.1016/S0092-8674(02)00899-1",

language = "English (US)",

volume = "110",

pages = "399--402",

journal = "Cell",

issn = "0092-8674",

publisher = "Cell Press",

number = "4",

}

TY - JOUR

T1 - Brain repair by endogenous progenitors

AU - Kruger, Genevieve M.

AU - Morrison, Sean J.

PY - 2002/8/23

Y1 - 2002/8/23

N2 - Stem cells within the adult brain can be stimulated by injury and growth factor treatment to replace damaged neurons, even neurons that are not normally generated in adults. Coupled with recent insights into the mechanism by which Nogo inhibits axonal regeneration, this discovery may inspire new treatments for central nervous system injuries and neurodegenerative diseases.

AB - Stem cells within the adult brain can be stimulated by injury and growth factor treatment to replace damaged neurons, even neurons that are not normally generated in adults. Coupled with recent insights into the mechanism by which Nogo inhibits axonal regeneration, this discovery may inspire new treatments for central nervous system injuries and neurodegenerative diseases.

UR - http://www.scopus.com/inward/record.url?scp=0037162693&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037162693&partnerID=8YFLogxK

U2 - 10.1016/S0092-8674(02)00899-1

DO - 10.1016/S0092-8674(02)00899-1

M3 - Review article

C2 - 12202029

AN - SCOPUS:0037162693

SN - 0092-8674

VL - 110

SP - 399

EP - 402

JO - Cell

JF - Cell

IS - 4

ER -

Brain repair by endogenous progenitors

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this