Breast carcinoma treatment received by women with disabilities compared with women without disabilities

Mabel E. Caban, Margaret A. Nosek, Daniel Graves, Francisco J. Esteva, Marsha McNeese

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

BACKGROUND. Disability may make it difficult to lie fiat or abduct the arm to deliver radiation therapy, imposing a high risk for radiation-induced side effects or difficulty in positioning patients for mammography. The goal of the current study was to determine the differences in treatment options experienced by women with physical disabilities compared with those without disabilities. METHODS. Chart review of 234 women who underwent surgery for breast carcinoma between June and September 1998 in a national comprehensive cancer center was conducted. Thirty-nine of the women had physical disabilities; the remaining 195 women were without disabilities. Hierarchical logistic regression was used to determine whether women with disabilities were less likely than women without disabilities to be treated with breast-conservation surgery (BCS) or neoadjuvant chemotherapy. RESULTS. Women with disabilities underwent BCS 38% of the time, whereas women without disabilities underwent BCS 49% of the time. Neither the presence nor absence of disability (P = 0.146) nor patient age (P = 0.747) were found to be significant predictors of BCS. However, the disease stage at the time of the surgery was reported to be a significant predictor of BCS (P = 0.007). The group of patients with disabilities received neoadjuvant chemotherapy 13% of the time, whereas women without disabilities received it 29% of the time. Disability was not found to be a significant predictor of whether a patient received neoadjuvant chemotherapy. Using hierarchical logistic regression, patient age was found to be a significant predictor of neoadjuvant chemotherapy before the disease stage was entered into the regression equation. There were no data to support the hypothesis that breast carcinoma is at an advanced stage when diagnosed in women with disabilities. CONCLUSIONS. These findings are clinically significant in that they indicate that women with disabilities are less likely to undergo BCS and are less likely to receive neoadjuvant chemotherapy compared with women without disabilities, but the difference did not reach statistical significance. To the authors' knowledge, there are no data to support the hypothesis that disabled women are diagnosed at a more advanced stage of disease compared with women without disabilities.

Original languageEnglish (US)
Pages (from-to)1391-1396
Number of pages6
JournalCancer
Volume94
Issue number5
DOIs
StatePublished - Mar 1 2002

Fingerprint

Breast Neoplasms
Breast
Therapeutics
Drug Therapy
Logistic Models
Patient Positioning
Mammography
Arm
Radiotherapy
Radiation

Keywords

  • Breast neoplasm
  • Breast-conservation surgery (BCS)
  • Chemotherapy
  • Collagen vascular diseaseseases
  • Disability
  • Female
  • Lupus
  • Polio
  • Radiation
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Breast carcinoma treatment received by women with disabilities compared with women without disabilities. / Caban, Mabel E.; Nosek, Margaret A.; Graves, Daniel; Esteva, Francisco J.; McNeese, Marsha.

In: Cancer, Vol. 94, No. 5, 01.03.2002, p. 1391-1396.

Research output: Contribution to journalArticle

Caban, Mabel E. ; Nosek, Margaret A. ; Graves, Daniel ; Esteva, Francisco J. ; McNeese, Marsha. / Breast carcinoma treatment received by women with disabilities compared with women without disabilities. In: Cancer. 2002 ; Vol. 94, No. 5. pp. 1391-1396.
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title = "Breast carcinoma treatment received by women with disabilities compared with women without disabilities",
abstract = "BACKGROUND. Disability may make it difficult to lie fiat or abduct the arm to deliver radiation therapy, imposing a high risk for radiation-induced side effects or difficulty in positioning patients for mammography. The goal of the current study was to determine the differences in treatment options experienced by women with physical disabilities compared with those without disabilities. METHODS. Chart review of 234 women who underwent surgery for breast carcinoma between June and September 1998 in a national comprehensive cancer center was conducted. Thirty-nine of the women had physical disabilities; the remaining 195 women were without disabilities. Hierarchical logistic regression was used to determine whether women with disabilities were less likely than women without disabilities to be treated with breast-conservation surgery (BCS) or neoadjuvant chemotherapy. RESULTS. Women with disabilities underwent BCS 38{\%} of the time, whereas women without disabilities underwent BCS 49{\%} of the time. Neither the presence nor absence of disability (P = 0.146) nor patient age (P = 0.747) were found to be significant predictors of BCS. However, the disease stage at the time of the surgery was reported to be a significant predictor of BCS (P = 0.007). The group of patients with disabilities received neoadjuvant chemotherapy 13{\%} of the time, whereas women without disabilities received it 29{\%} of the time. Disability was not found to be a significant predictor of whether a patient received neoadjuvant chemotherapy. Using hierarchical logistic regression, patient age was found to be a significant predictor of neoadjuvant chemotherapy before the disease stage was entered into the regression equation. There were no data to support the hypothesis that breast carcinoma is at an advanced stage when diagnosed in women with disabilities. CONCLUSIONS. These findings are clinically significant in that they indicate that women with disabilities are less likely to undergo BCS and are less likely to receive neoadjuvant chemotherapy compared with women without disabilities, but the difference did not reach statistical significance. To the authors' knowledge, there are no data to support the hypothesis that disabled women are diagnosed at a more advanced stage of disease compared with women without disabilities.",
keywords = "Breast neoplasm, Breast-conservation surgery (BCS), Chemotherapy, Collagen vascular diseaseseases, Disability, Female, Lupus, Polio, Radiation, Rheumatoid arthritis",
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T1 - Breast carcinoma treatment received by women with disabilities compared with women without disabilities

AU - Caban, Mabel E.

AU - Nosek, Margaret A.

AU - Graves, Daniel

AU - Esteva, Francisco J.

AU - McNeese, Marsha

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N2 - BACKGROUND. Disability may make it difficult to lie fiat or abduct the arm to deliver radiation therapy, imposing a high risk for radiation-induced side effects or difficulty in positioning patients for mammography. The goal of the current study was to determine the differences in treatment options experienced by women with physical disabilities compared with those without disabilities. METHODS. Chart review of 234 women who underwent surgery for breast carcinoma between June and September 1998 in a national comprehensive cancer center was conducted. Thirty-nine of the women had physical disabilities; the remaining 195 women were without disabilities. Hierarchical logistic regression was used to determine whether women with disabilities were less likely than women without disabilities to be treated with breast-conservation surgery (BCS) or neoadjuvant chemotherapy. RESULTS. Women with disabilities underwent BCS 38% of the time, whereas women without disabilities underwent BCS 49% of the time. Neither the presence nor absence of disability (P = 0.146) nor patient age (P = 0.747) were found to be significant predictors of BCS. However, the disease stage at the time of the surgery was reported to be a significant predictor of BCS (P = 0.007). The group of patients with disabilities received neoadjuvant chemotherapy 13% of the time, whereas women without disabilities received it 29% of the time. Disability was not found to be a significant predictor of whether a patient received neoadjuvant chemotherapy. Using hierarchical logistic regression, patient age was found to be a significant predictor of neoadjuvant chemotherapy before the disease stage was entered into the regression equation. There were no data to support the hypothesis that breast carcinoma is at an advanced stage when diagnosed in women with disabilities. CONCLUSIONS. These findings are clinically significant in that they indicate that women with disabilities are less likely to undergo BCS and are less likely to receive neoadjuvant chemotherapy compared with women without disabilities, but the difference did not reach statistical significance. To the authors' knowledge, there are no data to support the hypothesis that disabled women are diagnosed at a more advanced stage of disease compared with women without disabilities.

AB - BACKGROUND. Disability may make it difficult to lie fiat or abduct the arm to deliver radiation therapy, imposing a high risk for radiation-induced side effects or difficulty in positioning patients for mammography. The goal of the current study was to determine the differences in treatment options experienced by women with physical disabilities compared with those without disabilities. METHODS. Chart review of 234 women who underwent surgery for breast carcinoma between June and September 1998 in a national comprehensive cancer center was conducted. Thirty-nine of the women had physical disabilities; the remaining 195 women were without disabilities. Hierarchical logistic regression was used to determine whether women with disabilities were less likely than women without disabilities to be treated with breast-conservation surgery (BCS) or neoadjuvant chemotherapy. RESULTS. Women with disabilities underwent BCS 38% of the time, whereas women without disabilities underwent BCS 49% of the time. Neither the presence nor absence of disability (P = 0.146) nor patient age (P = 0.747) were found to be significant predictors of BCS. However, the disease stage at the time of the surgery was reported to be a significant predictor of BCS (P = 0.007). The group of patients with disabilities received neoadjuvant chemotherapy 13% of the time, whereas women without disabilities received it 29% of the time. Disability was not found to be a significant predictor of whether a patient received neoadjuvant chemotherapy. Using hierarchical logistic regression, patient age was found to be a significant predictor of neoadjuvant chemotherapy before the disease stage was entered into the regression equation. There were no data to support the hypothesis that breast carcinoma is at an advanced stage when diagnosed in women with disabilities. CONCLUSIONS. These findings are clinically significant in that they indicate that women with disabilities are less likely to undergo BCS and are less likely to receive neoadjuvant chemotherapy compared with women without disabilities, but the difference did not reach statistical significance. To the authors' knowledge, there are no data to support the hypothesis that disabled women are diagnosed at a more advanced stage of disease compared with women without disabilities.

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KW - Collagen vascular diseaseseases

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KW - Lupus

KW - Polio

KW - Radiation

KW - Rheumatoid arthritis

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