Breath-hold single-dose gadolinium-enhanced three-dimensional MR aortography: Usefulness of a timing examination and MR power injector

James P. Earls, Neil M. Rofsky, Douglas R. DeCorato, Glenn A. Krinsky, Jeffrey C. Weinreb

Research output: Contribution to journalArticle

308 Citations (Scopus)

Abstract

PURPOSE: To determine the usefulness of a timing examination performed with 1 mL gadopentetate dimeglumine administered with a magnetic resonance (MR) power injector at single-dose three-dimensional (3D) MR aortography. MATERIALS AND METHODS: 3D fast imaging with steady-state precession (repetition time [msec]/echo time [msec] = 5.0/2.0, with 50° flip angle) was performed in 30 patients after administration of 0.1 mmol/kg gadopentetate dimeglumine. In 15 inpatients, a power injector was used and a timing examination was performed (experimental group). In 15 outpatients, manual injection was used and a timing examination was not performed (control group). In the timing examination, 1 mL gadopentetate dimeglumine was followed with 15 mL saline, both at 2 mL/sec, during axial turbo fast low- angle shot imaging (11/4.2/300 [inversion time {msec}], with a 15° flip angle); one image was obtained every 2 seconds for 60 seconds. Aortic signal- to-noise ratios (S/Ns) and contrast-to-noise ratios (C/Ns) were determined on images obtained in the two groups. RESULTS: In the timing examinations, aortic S/N increased significantly (902% ± 517 [P < .001]) and was sufficient to help determine the timing of arterial enhancement. Findings on experimental images were superior to those on control images (S/N, 29.8 vs 20.5 [P = .003]; C/N, 23.8 vs 12.8 [P < .001], respectively). The time to perform procedures and calculations at the timing examination added a mean of 4.5 minutes to each examination. CONCLUSION: The combined use of a power injector and a timing examination improved S/Ns and C/Ns at breath-hold single-dose gadolinium-enhanced 3D MR aortography.

Original languageEnglish (US)
Pages (from-to)705-710
Number of pages6
JournalRadiology
Volume201
Issue number3
StatePublished - Dec 1996

Fingerprint

Aortography
Gadolinium
Gadolinium DTPA
Magnetic Resonance Spectroscopy
Noise
Signal-To-Noise Ratio
Inpatients
Outpatients
Control Groups
Injections

Keywords

  • Aorta, MR
  • Gadolinium
  • Magnetic resonance (MR), motion correction
  • Magnetic resonance (MR), pulse sequences
  • Magnetic resonance (MR), vascular studies

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Breath-hold single-dose gadolinium-enhanced three-dimensional MR aortography : Usefulness of a timing examination and MR power injector. / Earls, James P.; Rofsky, Neil M.; DeCorato, Douglas R.; Krinsky, Glenn A.; Weinreb, Jeffrey C.

In: Radiology, Vol. 201, No. 3, 12.1996, p. 705-710.

Research output: Contribution to journalArticle

Earls, James P. ; Rofsky, Neil M. ; DeCorato, Douglas R. ; Krinsky, Glenn A. ; Weinreb, Jeffrey C. / Breath-hold single-dose gadolinium-enhanced three-dimensional MR aortography : Usefulness of a timing examination and MR power injector. In: Radiology. 1996 ; Vol. 201, No. 3. pp. 705-710.
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abstract = "PURPOSE: To determine the usefulness of a timing examination performed with 1 mL gadopentetate dimeglumine administered with a magnetic resonance (MR) power injector at single-dose three-dimensional (3D) MR aortography. MATERIALS AND METHODS: 3D fast imaging with steady-state precession (repetition time [msec]/echo time [msec] = 5.0/2.0, with 50° flip angle) was performed in 30 patients after administration of 0.1 mmol/kg gadopentetate dimeglumine. In 15 inpatients, a power injector was used and a timing examination was performed (experimental group). In 15 outpatients, manual injection was used and a timing examination was not performed (control group). In the timing examination, 1 mL gadopentetate dimeglumine was followed with 15 mL saline, both at 2 mL/sec, during axial turbo fast low- angle shot imaging (11/4.2/300 [inversion time {msec}], with a 15° flip angle); one image was obtained every 2 seconds for 60 seconds. Aortic signal- to-noise ratios (S/Ns) and contrast-to-noise ratios (C/Ns) were determined on images obtained in the two groups. RESULTS: In the timing examinations, aortic S/N increased significantly (902{\%} ± 517 [P < .001]) and was sufficient to help determine the timing of arterial enhancement. Findings on experimental images were superior to those on control images (S/N, 29.8 vs 20.5 [P = .003]; C/N, 23.8 vs 12.8 [P < .001], respectively). The time to perform procedures and calculations at the timing examination added a mean of 4.5 minutes to each examination. CONCLUSION: The combined use of a power injector and a timing examination improved S/Ns and C/Ns at breath-hold single-dose gadolinium-enhanced 3D MR aortography.",
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T1 - Breath-hold single-dose gadolinium-enhanced three-dimensional MR aortography

T2 - Usefulness of a timing examination and MR power injector

AU - Earls, James P.

AU - Rofsky, Neil M.

AU - DeCorato, Douglas R.

AU - Krinsky, Glenn A.

AU - Weinreb, Jeffrey C.

PY - 1996/12

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N2 - PURPOSE: To determine the usefulness of a timing examination performed with 1 mL gadopentetate dimeglumine administered with a magnetic resonance (MR) power injector at single-dose three-dimensional (3D) MR aortography. MATERIALS AND METHODS: 3D fast imaging with steady-state precession (repetition time [msec]/echo time [msec] = 5.0/2.0, with 50° flip angle) was performed in 30 patients after administration of 0.1 mmol/kg gadopentetate dimeglumine. In 15 inpatients, a power injector was used and a timing examination was performed (experimental group). In 15 outpatients, manual injection was used and a timing examination was not performed (control group). In the timing examination, 1 mL gadopentetate dimeglumine was followed with 15 mL saline, both at 2 mL/sec, during axial turbo fast low- angle shot imaging (11/4.2/300 [inversion time {msec}], with a 15° flip angle); one image was obtained every 2 seconds for 60 seconds. Aortic signal- to-noise ratios (S/Ns) and contrast-to-noise ratios (C/Ns) were determined on images obtained in the two groups. RESULTS: In the timing examinations, aortic S/N increased significantly (902% ± 517 [P < .001]) and was sufficient to help determine the timing of arterial enhancement. Findings on experimental images were superior to those on control images (S/N, 29.8 vs 20.5 [P = .003]; C/N, 23.8 vs 12.8 [P < .001], respectively). The time to perform procedures and calculations at the timing examination added a mean of 4.5 minutes to each examination. CONCLUSION: The combined use of a power injector and a timing examination improved S/Ns and C/Ns at breath-hold single-dose gadolinium-enhanced 3D MR aortography.

AB - PURPOSE: To determine the usefulness of a timing examination performed with 1 mL gadopentetate dimeglumine administered with a magnetic resonance (MR) power injector at single-dose three-dimensional (3D) MR aortography. MATERIALS AND METHODS: 3D fast imaging with steady-state precession (repetition time [msec]/echo time [msec] = 5.0/2.0, with 50° flip angle) was performed in 30 patients after administration of 0.1 mmol/kg gadopentetate dimeglumine. In 15 inpatients, a power injector was used and a timing examination was performed (experimental group). In 15 outpatients, manual injection was used and a timing examination was not performed (control group). In the timing examination, 1 mL gadopentetate dimeglumine was followed with 15 mL saline, both at 2 mL/sec, during axial turbo fast low- angle shot imaging (11/4.2/300 [inversion time {msec}], with a 15° flip angle); one image was obtained every 2 seconds for 60 seconds. Aortic signal- to-noise ratios (S/Ns) and contrast-to-noise ratios (C/Ns) were determined on images obtained in the two groups. RESULTS: In the timing examinations, aortic S/N increased significantly (902% ± 517 [P < .001]) and was sufficient to help determine the timing of arterial enhancement. Findings on experimental images were superior to those on control images (S/N, 29.8 vs 20.5 [P = .003]; C/N, 23.8 vs 12.8 [P < .001], respectively). The time to perform procedures and calculations at the timing examination added a mean of 4.5 minutes to each examination. CONCLUSION: The combined use of a power injector and a timing examination improved S/Ns and C/Ns at breath-hold single-dose gadolinium-enhanced 3D MR aortography.

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KW - Gadolinium

KW - Magnetic resonance (MR), motion correction

KW - Magnetic resonance (MR), pulse sequences

KW - Magnetic resonance (MR), vascular studies

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