Bryostatin: A novel asymmetric synthesis of the C27-C34 fragment starting from (R)-carvone as chiral template

J. De Brabander, B. A. Kulkarni, R. Garcia-Lopez, M. Vandewalle

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

(R)-Carvone is a suitable chiral template for the synthesis of differently protected (4S,6R,7R)-trihydroxy-1-octyne derivatives, the C27-C34 fragment of bryostatins. Also other potentially interesting chiral building blocks are described.

Original languageEnglish (US)
Pages (from-to)1721-1724
Number of pages4
JournalTetrahedron Asymmetry
Volume8
Issue number11
DOIs
StatePublished - Jun 12 1997

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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