Bryostatins: The asymmetric synthesis of C1-C9 and C11-C16 fragments

J. De Brabander, K. Vanhessche, M. Vandewalle

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Abstract

The fragments C1-C9 19 and C11-C16 26 of the bryostatins are constructed in an enantioselective and highly diastereoselective fashion from respectively D-pantolactone (2) and L-erythrulose (3) as chiral templates.

Original languageEnglish (US)
Pages (from-to)2821-2824
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number24
DOIs
StatePublished - Jun 10 1991

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ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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