Bryostatins: The asymmetric synthesis of C1-C9 and C11-C16 fragments

J. De Brabander, K. Vanhessche, M. Vandewalle

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

The fragments C1-C9 19 and C11-C16 26 of the bryostatins are constructed in an enantioselective and highly diastereoselective fashion from respectively D-pantolactone (2) and L-erythrulose (3) as chiral templates.

Original languageEnglish (US)
Pages (from-to)2821-2824
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number24
DOIs
StatePublished - Jun 10 1991

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Bryostatins
erythrulose
pantolactone

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Bryostatins : The asymmetric synthesis of C1-C9 and C11-C16 fragments. / De Brabander, J.; Vanhessche, K.; Vandewalle, M.

In: Tetrahedron Letters, Vol. 32, No. 24, 10.06.1991, p. 2821-2824.

Research output: Contribution to journalArticle

De Brabander, J. ; Vanhessche, K. ; Vandewalle, M. / Bryostatins : The asymmetric synthesis of C1-C9 and C11-C16 fragments. In: Tetrahedron Letters. 1991 ; Vol. 32, No. 24. pp. 2821-2824.
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