Bryostatins: The asymmetric synthesis of C1-C9 and C11-C16 fragments

J. De Brabander; K. Vanhessche; M. Vandewalle

doi:10.1016/0040-4039(91)85096-N

Bryostatins: The asymmetric synthesis of C₁-C₉ and C₁₁-C₁₆ fragments

J. De Brabander, K. Vanhessche, M. Vandewalle

Research output: Contribution to journal › Article › peer-review

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Abstract

The fragments C₁-C₉ 19 and C₁₁-C₁₆ 26 of the bryostatins are constructed in an enantioselective and highly diastereoselective fashion from respectively D-pantolactone (2) and L-erythrulose (3) as chiral templates.

Original language	English (US)
Pages (from-to)	2821-2824
Number of pages	4
Journal	Tetrahedron Letters
Volume	32
Issue number	24
DOIs	https://doi.org/10.1016/0040-4039(91)85096-N
State	Published - Jun 10 1991

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/0040-4039(91)85096-N

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title = "Bryostatins: The asymmetric synthesis of C1-C9 and C11-C16 fragments",

abstract = "The fragments C1-C9 19 and C11-C16 26 of the bryostatins are constructed in an enantioselective and highly diastereoselective fashion from respectively D-pantolactone (2) and L-erythrulose (3) as chiral templates.",

author = "{De Brabander}, J. and K. Vanhessche and M. Vandewalle",

year = "1991",

month = jun,

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doi = "10.1016/0040-4039(91)85096-N",

language = "English (US)",

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TY - JOUR

T1 - Bryostatins

T2 - The asymmetric synthesis of C1-C9 and C11-C16 fragments

AU - De Brabander, J.

AU - Vanhessche, K.

AU - Vandewalle, M.

PY - 1991/6/10

Y1 - 1991/6/10

N2 - The fragments C1-C9 19 and C11-C16 26 of the bryostatins are constructed in an enantioselective and highly diastereoselective fashion from respectively D-pantolactone (2) and L-erythrulose (3) as chiral templates.

AB - The fragments C1-C9 19 and C11-C16 26 of the bryostatins are constructed in an enantioselective and highly diastereoselective fashion from respectively D-pantolactone (2) and L-erythrulose (3) as chiral templates.

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U2 - 10.1016/0040-4039(91)85096-N

DO - 10.1016/0040-4039(91)85096-N

M3 - Article

AN - SCOPUS:0025804978

SN - 0040-4039

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 24

ER -

Bryostatins: The asymmetric synthesis of C₁-C₉ and C₁₁-C₁₆ fragments

Abstract

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