C-reactive protein and cardiac vagal activity following resistance exercise training in young African-American and white men

Kevin S. Heffernan, Sae Young Jae, Victoria J. Vieira, Gary A. Iwamoto, Kenneth R. Wilund, Jeffrey A. Woods, Bo Fernhall

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

African Americans have a greater prevalence of hypertension and diabetes compared with white Americans, and both autonomic dysregulation and inflammation have been implicated in the etiology of these disease states. The purpose of this study was to examine the cardiac autonomic and systemic inflammatory response to resistance training in young African-American and white men. Linear (time and frequency domain) and nonlinear (sample entropy) heart rate variability, baroreflex sensitivity, tonic and reflex vagal activity, and postexercise heart rate recovery were used to assess cardiac vagal modulation. C-reactive protein (CRP) and white blood cell count were used as inflammatory markers. Twenty two white and 19 African-American men completed 6 wk of resistance training followed by 4 wk of exercise detraining (Post 2). Sample entropy, tonic and reflex vagal activity, and heart rate recovery were increased in white and African-American men following resistance training (P < 0.05). Following detraining (Post 2), sample entropy, tonic and reflex vagal activity, and heart rate recovery returned to baseline values in white men but remained above baseline in African-American men. While there were no changes in white blood cell count or CRP in white men, these inflammatory markers decreased in African-American men following resistance training, with reductions being maintained following detraining (P < 0.05). In conclusion, resistance training improves cardiac autonomic function and reduces inflammation in African-American men, and these adaptations remained after the cessation of training. Resistance training may be an important lifestyle modification for improving cardiac autonomic health and reducing inflammation in young African-American men.

Original languageEnglish (US)
JournalAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology
Volume296
Issue number4
DOIs
StatePublished - Apr 2009

Fingerprint

Resistance Training
African Americans
C-Reactive Protein
Exercise
Entropy
Heart Rate
Reflex
Inflammation
Leukocyte Count
Baroreflex
Life Style
Hypertension
Health

Keywords

  • Exercise
  • Heart rate recovery
  • Heart rate variability
  • Inflammation

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

Cite this

C-reactive protein and cardiac vagal activity following resistance exercise training in young African-American and white men. / Heffernan, Kevin S.; Jae, Sae Young; Vieira, Victoria J.; Iwamoto, Gary A.; Wilund, Kenneth R.; Woods, Jeffrey A.; Fernhall, Bo.

In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology, Vol. 296, No. 4, 04.2009.

Research output: Contribution to journalArticle

@article{ceebc73e51aa415192d94e006d0f62d6,
title = "C-reactive protein and cardiac vagal activity following resistance exercise training in young African-American and white men",
abstract = "African Americans have a greater prevalence of hypertension and diabetes compared with white Americans, and both autonomic dysregulation and inflammation have been implicated in the etiology of these disease states. The purpose of this study was to examine the cardiac autonomic and systemic inflammatory response to resistance training in young African-American and white men. Linear (time and frequency domain) and nonlinear (sample entropy) heart rate variability, baroreflex sensitivity, tonic and reflex vagal activity, and postexercise heart rate recovery were used to assess cardiac vagal modulation. C-reactive protein (CRP) and white blood cell count were used as inflammatory markers. Twenty two white and 19 African-American men completed 6 wk of resistance training followed by 4 wk of exercise detraining (Post 2). Sample entropy, tonic and reflex vagal activity, and heart rate recovery were increased in white and African-American men following resistance training (P < 0.05). Following detraining (Post 2), sample entropy, tonic and reflex vagal activity, and heart rate recovery returned to baseline values in white men but remained above baseline in African-American men. While there were no changes in white blood cell count or CRP in white men, these inflammatory markers decreased in African-American men following resistance training, with reductions being maintained following detraining (P < 0.05). In conclusion, resistance training improves cardiac autonomic function and reduces inflammation in African-American men, and these adaptations remained after the cessation of training. Resistance training may be an important lifestyle modification for improving cardiac autonomic health and reducing inflammation in young African-American men.",
keywords = "Exercise, Heart rate recovery, Heart rate variability, Inflammation",
author = "Heffernan, {Kevin S.} and Jae, {Sae Young} and Vieira, {Victoria J.} and Iwamoto, {Gary A.} and Wilund, {Kenneth R.} and Woods, {Jeffrey A.} and Bo Fernhall",
year = "2009",
month = "4",
doi = "10.1152/ajpregu.90936.2008",
language = "English (US)",
volume = "296",
journal = "American Journal of Physiology - Heart and Circulatory Physiology",
issn = "0363-6135",
publisher = "American Physiological Society",
number = "4",

}

TY - JOUR

T1 - C-reactive protein and cardiac vagal activity following resistance exercise training in young African-American and white men

AU - Heffernan, Kevin S.

AU - Jae, Sae Young

AU - Vieira, Victoria J.

AU - Iwamoto, Gary A.

AU - Wilund, Kenneth R.

AU - Woods, Jeffrey A.

AU - Fernhall, Bo

PY - 2009/4

Y1 - 2009/4

N2 - African Americans have a greater prevalence of hypertension and diabetes compared with white Americans, and both autonomic dysregulation and inflammation have been implicated in the etiology of these disease states. The purpose of this study was to examine the cardiac autonomic and systemic inflammatory response to resistance training in young African-American and white men. Linear (time and frequency domain) and nonlinear (sample entropy) heart rate variability, baroreflex sensitivity, tonic and reflex vagal activity, and postexercise heart rate recovery were used to assess cardiac vagal modulation. C-reactive protein (CRP) and white blood cell count were used as inflammatory markers. Twenty two white and 19 African-American men completed 6 wk of resistance training followed by 4 wk of exercise detraining (Post 2). Sample entropy, tonic and reflex vagal activity, and heart rate recovery were increased in white and African-American men following resistance training (P < 0.05). Following detraining (Post 2), sample entropy, tonic and reflex vagal activity, and heart rate recovery returned to baseline values in white men but remained above baseline in African-American men. While there were no changes in white blood cell count or CRP in white men, these inflammatory markers decreased in African-American men following resistance training, with reductions being maintained following detraining (P < 0.05). In conclusion, resistance training improves cardiac autonomic function and reduces inflammation in African-American men, and these adaptations remained after the cessation of training. Resistance training may be an important lifestyle modification for improving cardiac autonomic health and reducing inflammation in young African-American men.

AB - African Americans have a greater prevalence of hypertension and diabetes compared with white Americans, and both autonomic dysregulation and inflammation have been implicated in the etiology of these disease states. The purpose of this study was to examine the cardiac autonomic and systemic inflammatory response to resistance training in young African-American and white men. Linear (time and frequency domain) and nonlinear (sample entropy) heart rate variability, baroreflex sensitivity, tonic and reflex vagal activity, and postexercise heart rate recovery were used to assess cardiac vagal modulation. C-reactive protein (CRP) and white blood cell count were used as inflammatory markers. Twenty two white and 19 African-American men completed 6 wk of resistance training followed by 4 wk of exercise detraining (Post 2). Sample entropy, tonic and reflex vagal activity, and heart rate recovery were increased in white and African-American men following resistance training (P < 0.05). Following detraining (Post 2), sample entropy, tonic and reflex vagal activity, and heart rate recovery returned to baseline values in white men but remained above baseline in African-American men. While there were no changes in white blood cell count or CRP in white men, these inflammatory markers decreased in African-American men following resistance training, with reductions being maintained following detraining (P < 0.05). In conclusion, resistance training improves cardiac autonomic function and reduces inflammation in African-American men, and these adaptations remained after the cessation of training. Resistance training may be an important lifestyle modification for improving cardiac autonomic health and reducing inflammation in young African-American men.

KW - Exercise

KW - Heart rate recovery

KW - Heart rate variability

KW - Inflammation

UR - http://www.scopus.com/inward/record.url?scp=66049086970&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=66049086970&partnerID=8YFLogxK

U2 - 10.1152/ajpregu.90936.2008

DO - 10.1152/ajpregu.90936.2008

M3 - Article

C2 - 19193941

AN - SCOPUS:66049086970

VL - 296

JO - American Journal of Physiology - Heart and Circulatory Physiology

JF - American Journal of Physiology - Heart and Circulatory Physiology

SN - 0363-6135

IS - 4

ER -