Abstract
In response to invasive stimuli, macrophages secrete cachectin, a multipotent protein. Prominent among its biological effects is the ability to induce wasting (cachexia) as well as a lethal state of shock. The identity of cachectin and tumour necrosis factor has led to a new view of its therapeutic potential.
Original language | English (US) |
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Pages (from-to) | 584-588 |
Number of pages | 5 |
Journal | Nature |
Volume | 320 |
Issue number | 6063 |
DOIs | |
State | Published - 1986 |
ASJC Scopus subject areas
- General