Cone beam breast CT technique provides true three dimensional (3D) images of breast anatomy; however the detectability of calcification is limited due to low exposure levels on each projection. In this study, we investigated the possibility of using anisotropic exposure distributions to improve the visibility of calcifications in the breast CT images. Our approach was to measure the CBCT projections with isotropic high and low exposures separately. Reconstruction was performed upon different combinations of these two sets of projection sequences to investigate the visibility change due to the limited-angle high exposure projections. Our preliminary results show that the visibility is improved with the number of high exposure projections in the combinations. In the future we will measure the CBCT projections with anisotropic exposures while keeping the total exposure constant.