Can We Be Too Clean for Our Own Good? The Hygiene Hypothesis Reviewed

Sheenal Patel, Rebecca Gruchalla

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The hygiene hypothesis began as an attempt to explain the relatively rapid rise in atopic diseases. Strachan's early hypothesis regarding the role of family size and exposure to early childhood infections in the development of atopic diseases has clearly evolved to integrate the possible effects of hygiene, eradication of parasitic infections, immunizations, improvements in home heating and ventilation, dust mite exposure, breastfeeding duration, diet, parental smoking, pollution, and exposure to pets and farm animals. However, as most of our understanding at the current time still comes from observational and epidemiologic studies, further investigations are needed to help uncover which of these genetic and environmental factors are indeed the causes behind the increases in allergic rhinitis and asthma.

Original languageEnglish (US)
Pages (from-to)54-59
Number of pages6
JournalTexas Medicine
Volume113
Issue number2
StatePublished - Feb 1 2017

Fingerprint

Hygiene Hypothesis
Parasitic Diseases
Mites
Pets
Domestic Animals
Breast Feeding
Dust
Hygiene
Heating
Observational Studies
Ventilation
Epidemiologic Studies
Immunization
Asthma
Smoking
Diet
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Can We Be Too Clean for Our Own Good? The Hygiene Hypothesis Reviewed. / Patel, Sheenal; Gruchalla, Rebecca.

In: Texas Medicine, Vol. 113, No. 2, 01.02.2017, p. 54-59.

Research output: Contribution to journalArticle

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