Cardiac changes to signalled shock avoidance in dogs

Richard A. Galosy, Lewis K. Clarke, Jere H. Mitchell

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Alterations in heart rate (HR), left ventricular pressure (LVP), and maximum left ventricular dp/dt (LVdp/dt max) during a signalled avoidance task were studied in eight chronically prepared dogs. Four of these animals comprised a non-shock control group. In experimental animals, HR increased during the first two days of the avoidance task but did not change significantly during the last two days, while LVP remained at the supranormal post-training levels and LVdp/dt max increased over the course of the experiment. Control animals showed no change in HR or LVP, but LVdp/dt max decreased over the four experimental days. Changes in LVdp/dt max in experimentals reflect a consistent increase in cardiac sympathetic activation. However, HR changes indicate an initial increase and a subsequent decrease in sympathetic activity. It was therefore postulated that either differential activation of sympathetic cardiac fibers occurred such that during non-stress periods and subsequent exposure to stress, sympathetic influences predominate which are reflected only in LVdp/dt max changes, or sympathetic and parasympathetic fibers differentially control cardiac function during stress and non-stress conditions.

Original languageEnglish (US)
Pages (from-to)33-38
Number of pages6
JournalPhysiology and Behavior
Volume21
Issue number1
DOIs
StatePublished - Jul 1978

Keywords

  • Autonomic nervous system
  • Dogs
  • Heart rate
  • Left ventricular dp/dt
  • Left ventricular pressure
  • Signalled avoidance

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

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