Cardiac effects of diphenylhydantoin (Dilantin) in man

Donald S. Mierzwiak; William Shapiro; Michael C. McNalley; Jere H. Mitchell

doi:10.1016/0002-9149(68)90008-8

Cardiac effects of diphenylhydantoin (Dilantin) in man

Donald S. Mierzwiak, William Shapiro, Michael C. McNalley, Jere H. Mitchell

Research output: Contribution to journal › Article

4 Scopus citations

Abstract

The effect of Dilantin (diphenylhydantoin sodium) on right ventricular function was evaluated in 5 patients undergoing diagnostic cardiac catheterization. A transient negative inotropic effect on the right ventricle and an apparently induced conduction disturbance were seen following administration of Dilantin. Nausea, vomiting and hypotension were also associated with the administration of Dilantin. These findings emphasize the need for more information in order to properly utilize Dilantin as an antiarrhythmic agent.

Original language	English (US)
Pages (from-to)	20-22
Number of pages	3
Journal	The American journal of cardiology
Volume	21
Issue number	1
DOIs	https://doi.org/10.1016/0002-9149(68)90008-8
State	Published - Jan 1968

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/0002-9149(68)90008-8

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Mierzwiak, D. S., Shapiro, W., McNalley, M. C., & Mitchell, J. H. (1968). Cardiac effects of diphenylhydantoin (Dilantin) in man. The American journal of cardiology, 21(1), 20-22. https://doi.org/10.1016/0002-9149(68)90008-8

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