TY - JOUR
T1 - Cardiac Implantable Electronic Devices Following Heart Transplantation
AU - DeFilippis, Ersilia M.
AU - Rubin, Geoffrey
AU - Farr, Maryjane A.
AU - Biviano, Angelo
AU - Wan, Elaine Y.
AU - Takeda, Koji
AU - Garan, Hasan
AU - Topkara, Veli K.
AU - Yarmohammadi, Hirad
N1 - Publisher Copyright:
© 2020 American College of Cardiology Foundation
PY - 2020/8
Y1 - 2020/8
N2 - Permanent pacemaker (PPM) implantation is required in a subset of patients (∼10%) for sinus node dysfunction or atrioventricular block both early and late after heart transplantation. The incidence of PPM implantation has decreased to <5% with the advent of bicaval anastamosis transplantation surgery. Pacing dependence upon follow-up has been variably reported. An even smaller percentage of transplantation recipients (1.5% to 3.4%) undergo implantable cardioverter-defibrillator (ICD) placement. Rigorous data are lacking for the use of ICDs in the transplantation population and is largely derived from cohort studies and case series. Sudden cardiac death occurs in approximately 10% of transplantation recipients, but multiple nonarrhythmic factors are believed to be responsible, including acute rejection, late graft failure with electromechanical dissociation, and ischemia due to cardiac allograft vasculopathy. This review provides a comprehensive analysis of the existing data regarding the role for PPMs and ICDs in this population, including leadless PPMs and subcutaneous ICDs, special considerations, and future directions.
AB - Permanent pacemaker (PPM) implantation is required in a subset of patients (∼10%) for sinus node dysfunction or atrioventricular block both early and late after heart transplantation. The incidence of PPM implantation has decreased to <5% with the advent of bicaval anastamosis transplantation surgery. Pacing dependence upon follow-up has been variably reported. An even smaller percentage of transplantation recipients (1.5% to 3.4%) undergo implantable cardioverter-defibrillator (ICD) placement. Rigorous data are lacking for the use of ICDs in the transplantation population and is largely derived from cohort studies and case series. Sudden cardiac death occurs in approximately 10% of transplantation recipients, but multiple nonarrhythmic factors are believed to be responsible, including acute rejection, late graft failure with electromechanical dissociation, and ischemia due to cardiac allograft vasculopathy. This review provides a comprehensive analysis of the existing data regarding the role for PPMs and ICDs in this population, including leadless PPMs and subcutaneous ICDs, special considerations, and future directions.
KW - heart transplantation
KW - implantable cardioverter-defibrillator
KW - pacemaker
KW - sudden cardiac death
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U2 - 10.1016/j.jacep.2020.06.023
DO - 10.1016/j.jacep.2020.06.023
M3 - Review article
C2 - 32819520
AN - SCOPUS:85089280300
SN - 2405-500X
VL - 6
SP - 1028
EP - 1042
JO - JACC: Clinical Electrophysiology
JF - JACC: Clinical Electrophysiology
IS - 8
ER -