Cardiac Risk After Craniopharyngioma Therapy

Sandy Mong, Scott L. Pomeroy, Frank Cecchin, Amy Juraszek, Mark E. Alexander

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Although long-term survival after craniopharyngioma treatment is excellent in childhood and early adulthood, sudden deaths in two craniopharyngioma survivors with cardiac findings suggest a need to determine whether treated patients exhibit potential substrates for sudden cardiac death. We present a retrospective review of two index patients with cardiac mortality. This motivated a prospective cardiac screening of 12 survivors that identified nearly a third with significant QTc prolongation. QTc-prolonging medication and stimulants should be used with caution in this population, and routine electrocardiogram screening may identify those at highest risk.

Original languageEnglish (US)
Pages (from-to)256-260
Number of pages5
JournalPediatric Neurology
Volume38
Issue number4
DOIs
StatePublished - Apr 1 2008

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology

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    Mong, S., Pomeroy, S. L., Cecchin, F., Juraszek, A., & Alexander, M. E. (2008). Cardiac Risk After Craniopharyngioma Therapy. Pediatric Neurology, 38(4), 256-260. https://doi.org/10.1016/j.pediatrneurol.2007.11.007