Cardiovascular risk in diabetes mellitus: Complication of the disease or of antihyperglycemic medications

C. A. Alvarez, Ildiko Lingvay, V. Vuylsteke, R. L. Koffarnus, Darren K McGuire

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Cardiovascular disease is the principal complication and the leading cause of death for patients with diabetes (DM). The efficacy of antihyperglycemic treatments on cardiovascular disease risk remains uncertain. Cardiovascular risk factors are affected by antihyperglycemic medications, as are many intermediate markers of cardiovascular disease. Here we summarize the evidence assessing the cardiovascular effects of antihyperglycemic medications with regard to risk factors, intermediate markers of disease, and clinical outcomes.

Original languageEnglish (US)
Pages (from-to)145-161
Number of pages17
JournalClinical Pharmacology and Therapeutics
Volume98
Issue number2
DOIs
StatePublished - Aug 1 2015

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Medicine(all)

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