Carotid Arteries: Contrast-enhanced US Angiography-Preliminary Clinical Experience

Yuko Kono, Sean P. Pinnell, Claude B. Sirlin, Steven R. Sparks, Bassem Georgy, Wade Wong, Robert F. Mattrey

Research output: Contribution to journalArticle

75 Scopus citations

Abstract

B-mode ultrasonographic (US) angiography enhanced with a microbubble-based US contrast agent (FS069) was evaluated in human subjects with carotid artery disease. Results at contrast material-enhanced US angiography and duplex US were compared with those at conventional angiography. Both US angiography and duplex US accurately depicted stenoses of 70% or more compared with those depicted at conventional angiography. The percentage diameter stenosis of the internal carotid artery measured at US angiography strongly correlated with that measured at conventional angiography (r = 0.988). The percentage area stenosis measured at US angiography strongly correlated with ex vivo measurements of the resected carotid plaque at magnetic resonance imaging (r = 0.979). US angiography depicted unsuspected wall irregularities, ulceration, and dissection.

Original languageEnglish (US)
Pages (from-to)561-568
Number of pages8
JournalRADIOLOGY
Volume230
Issue number2
DOIs
StatePublished - Feb 1 2004

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Keywords

  • Carotid arteries, US
  • Carotid arteries, stenosis or obstruction
  • Ultrasound (US), contrast media

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Kono, Y., Pinnell, S. P., Sirlin, C. B., Sparks, S. R., Georgy, B., Wong, W., & Mattrey, R. F. (2004). Carotid Arteries: Contrast-enhanced US Angiography-Preliminary Clinical Experience. RADIOLOGY, 230(2), 561-568. https://doi.org/10.1148/radiol.2302020318