Catalytic enantioselective allylic amination of unactivated terminal olefins via an Ene reaction/[2,3]-rearrangement

Hongli Bao, Uttam K. Tambar

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

The enantioselective allylic amination of unactivated terminal olefins represents a direct and attractive strategy for the synthesis of enantioenriched amines. We have developed the first use of a nitrogen-containing reagent and a chiral palladium catalyst to convert unfunctionalized olefins into enantioenriched allylic amines via an ene reaction/[2,3]-rearrangement.

Original languageEnglish (US)
Pages (from-to)18495-18498
Number of pages4
JournalJournal of the American Chemical Society
Volume134
Issue number45
DOIs
StatePublished - Nov 14 2012

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Amination
Alkenes
Olefins
Amines
Palladium
Nitrogen
Catalysts

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Catalytic enantioselective allylic amination of unactivated terminal olefins via an Ene reaction/[2,3]-rearrangement. / Bao, Hongli; Tambar, Uttam K.

In: Journal of the American Chemical Society, Vol. 134, No. 45, 14.11.2012, p. 18495-18498.

Research output: Contribution to journalArticle

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