@article{be7b83a588e54c04b4dcbcf054dd2e55,
title = "Catechol-O-methyltransferase activity in erythrocytes of pregnant women with sickle cell disease before, during, and after transfusion and partial exchange transfusion",
abstract = "In the present investigation, we found that the catechol-O-methyltransferase (COMT) activity in erythrocytes of pregnant women with sickle cell disease was strikingly elevated compared with that in erythrocytes of men and pregnant and nonpregnant women. Moreover, the enzyme activity in erythrocytes remained high during and after transfusion or partial exchange transfusion even though the enzyme activity in donor cells was low. This finding is suggestive of the possibility that a factor(s) in plasma of persons with sickle cell disease activates erythrocyte COMT activity.",
author = "Cunningham, {F. Gary} and Susan Rawlins and Casey, {M. Linette} and MacDonald, {Paul C.}",
note = "Funding Information: Reprint requests: M. Linette Casey, Ph.D., The Cecil H. and Ia{\textquoteright}a Green Center for Reproductive Biology Sciences, The UniversiEy oj Texas Southwestern Medical School, 5323 Harry Hines Boule-vard, Dallas, Texas 75235. *Postdoctoral Trainee supported in part by United States Public Health Service Grant No. 1 -T32-HDO7190. Funding Information: This investigation was supported in part by United States Public Health Service Grant No. 5-P50-HDI 1149.",
year = "1983",
month = nov,
day = "1",
doi = "10.1016/0002-9378(83)90020-0",
language = "English (US)",
volume = "147",
pages = "573--575",
journal = "American journal of obstetrics and gynecology",
issn = "0002-9378",
publisher = "Mosby Inc.",
number = "5",
}