Caveolin-1 Expression in Upper Tract Urothelial Carcinoma

David D'Andrea, Marco Moschini, Beat Foerster, Mohammad Abufaraj, Vitaly Margulis, Jose Karam, Yair Lotan, Jay Raman, Romain Mathieu, Morgan Rouprêt, Pierre I. Karakiewicz, Alberto Briganti, Andrea Haitel, Sharhrokh F. Shariat

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Caveolin-1 is associated with worse oncological features among patients treated with radical nephroureterectomy for upper tract urothelial carcinoma (UTUC), but is not independently associated with oncological outcomes. Its clinical use could be explored in UTUC biopsy specimens for improving clinical staging and helping in decision-making regarding a kidney-sparing approach or neoadjuvant systemic treatment.

Original languageEnglish (US)
Pages (from-to)97-103
Number of pages7
JournalEuropean Urology Focus
Volume5
Issue number1
DOIs
StatePublished - Jan 2019

Keywords

  • Biomarker
  • Caveolin-1
  • Nephroureterectomy
  • Outcome
  • Upper tract urothelial carcinoma

ASJC Scopus subject areas

  • Urology

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