Cell cycle block and apoptosis induction in a human melanoma cell line following treatment with 2-methoxyoestradiol: Therapeutic implications?

Medicine & Life Sciences

• 2-Methoxyestradiol 100%
• Melanoma 52%
• Cell Cycle 50%
• Apoptosis 38%
• Cell Line 37%
• Growth 16%
• CDC2 Protein Kinase 15%
• Apoptosis Regulatory Proteins 12%
• G2 Phase 11%
• DNA Fragmentation 11%
• In Situ Nick-End Labeling 11%
• Therapeutics 10%
• Cell Division 10%
• Therapeutic Uses 8%
• Flow Cytometry 8%
• Cell Culture Techniques 8%
• Phosphorylation 7%
• Western Blotting 7%
• Staining and Labeling 6%