CENP-T bears the load in mitosis

Yang Yang, Hongtao Yu

Research output: Contribution to journalComment/debate

Abstract

During mitosis, the kinetochore connects chromosomes to spindle microtubules and enables chromosome segregation. A genetic study in vertebrate cells demonstrates phosphorylation-regulated plasticity of kinetochore assembly and highlights the role of the centromere protein T in load-bearing kinetochore–microtubule attachment.

Original languageEnglish (US)
Pages (from-to)1335-1337
Number of pages3
JournalNature Cell Biology
Volume20
Issue number12
DOIs
StatePublished - Dec 1 2018

ASJC Scopus subject areas

  • Cell Biology

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