Central nervous system infections in the intensive care unit

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Infections of the central nervous system are a frequent cause for admission to the intensive care unit (ICU). These infections can be the reason for presentation to a hospital or a complication of an injury or surgical procedure. Diagnosing these infections can be very challenging, given the relative paucity of tests with high sensitivity and specificity. Regardless, identifying and treating the underlying cause remains the primary objective in each of these cases, but management of complications is the most common reason for ICU admission. Frequent complications include increased intracranial pressure, stroke, coma, and status epilepticus. Although the underlying infection often causes harm, the immune response to the agent and ensuing complications are often responsible for greater damage to the host. Even if the underlying infectious agent does not have a specific therapy, identifying it is important for limiting unnecessary testing. When certain infections are suspected, such as bacterial meningitis or viral encephalitis, empiric therapy should be initiated immediately. Outcomes for these conditions are linked to how quickly appropriate therapies are initiated.

Original languageEnglish (US)
Pages (from-to)682-689
Number of pages8
JournalSeminars in Neurology
Volume28
Issue number5
DOIs
StatePublished - Nov 2008

Fingerprint

Central Nervous System Infections
Intensive Care Units
Infection
Viral Encephalitis
Bacterial Meningitides
Status Epilepticus
Intraoperative Complications
Intracranial Pressure
Case Management
Coma
Therapeutics
Stroke
Sensitivity and Specificity

Keywords

  • Brain abscess
  • Encephalitis
  • Infections
  • Meningitis
  • Myelitis
  • Postsurgical

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Central nervous system infections in the intensive care unit. / Greenberg, Benjamin M.

In: Seminars in Neurology, Vol. 28, No. 5, 11.2008, p. 682-689.

Research output: Contribution to journalArticle

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