Central nervous system lymphoma not detectable on single-photon emission CT with thallium 201

Dale C. Fisher, David P. Chason, Dana Mathews, Dennis K. Burns, James L. Fleckenstein

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

A 33-year-old man with acquired immunodeficiency syndrome had an erosive supraglottic mass visible on CT scans of the neck; biopsy was postponed because of the patient's debilitated condition. Two weeks later, he was admitted with altered mental status; an MR image of the brain obtained at that time showed multiple bilateral mass lesions, the largest of which was 5 cm. Findings on a thallium-201 single-photon emission CT (SPECT) scan of the brain were normal. Ten days later, the patient died end autopsy showed both the neck and the brain lesions to be large-cell lymphoma. This case is counterevidence to the reported 100% sensitivity of thallium-201 brain SPECT for demonstrating lymphoma of the central nervous system.

Original languageEnglish (US)
Pages (from-to)1687-1690
Number of pages4
JournalAmerican Journal of Neuroradiology
Volume17
Issue number9
StatePublished - Oct 1 1996

Keywords

  • Acquired immunodeficiency syndrome (AIDS)
  • Lymphoma
  • Single-photon emission computed tomography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

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