Cerebellar Control of Eye Movements

Shin C Beh, Teresa C. Frohman, Elliot Frohman

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

BACKGROUND:: The cerebellum plays a central role in the online, real-time control, and long-term modulation of eye movements. EVIDENCE ACQUISITION:: We reviewed the latest (fifth) edition of Leigh and Zeeʼs textbook, The Neurology of Eye Movements, and literature in PUBMED using the following terms: cerebellum, flocculus, paraflocculus, vermis, oculomotor vermis, dorsal vermis, caudal fastigial nucleus, fastigial oculomotor region, uvula, nodulus, ansiform lobule, eye movements, saccades, ipsipulsion, contrapulsion, smooth pursuit, vergence, convergence, divergence, gaze-holding, down beat nystagmus, vestibulo-ocular reflex (VOR), angular VOR, translational VOR, skew deviation, velocity storage. RESULTS:: The cerebellum is vital in optimizing the performance of all classes of gaze-shifting and gaze-stabilizing reflexes. The flocculus-paraflocculus are crucial to VOR gain and direction, pulse-step matching for saccades, pursuit gain, and gaze-holding. The oculomotor vermis and caudal fastigial nuclei are essential in saccadic adaptation and accuracy, and pursuit gain. The nodulus and ventral uvula are involved in processing otolothic signals and VOR responses, including velocity storage. CONCLUSIONS:: The cerebellum guarantees the precision of ocular movements to optimize visual performance and occupies a central role in all classes of eye movements both in real-time control and in long-term calibration and learning (i.e., adaptation).

Original languageEnglish (US)
JournalJournal of Neuro-Ophthalmology
DOIs
StateAccepted/In press - Sep 16 2016

Fingerprint

Vestibulo-Ocular Reflex
Eye Movements
Cerebellum
Uvula
Cerebellar Nuclei
Saccades
Smooth Pursuit
Ocular Motility Disorders
Textbooks
Neurology
Calibration
Reflex
Learning

ASJC Scopus subject areas

  • Medicine(all)
  • Ophthalmology
  • Clinical Neurology

Cite this

Cerebellar Control of Eye Movements. / Beh, Shin C; Frohman, Teresa C.; Frohman, Elliot.

In: Journal of Neuro-Ophthalmology, 16.09.2016.

Research output: Contribution to journalArticle

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