Cerebral near infrared spectroscopy is a reliable marker of systemic perfusion in awake single ventricle children

Paul M. Kirshbom, Joseph M. Forbess, Brian E. Kogon, Janet M. Simsic, Dennis W. Kim, Anthony A. Raviele, Kirk R. Kanter, Robert N. Vincent

Research output: Contribution to journalArticle

30 Scopus citations


Clinical assessment of systemic perfusion in single ventricle patients with parallel circulation can be difficult in the outpatient setting. Near infrared spectroscopy (NIRS) is a noninvasive measure of cerebral oximetry. We measured vital signs, pulse oximetry, and NIRS in 20 single ventricle patients with parallel circulation prior to routine cardiac catheterization. These variables were evaluated to determine the best noninvasive predictor of the superior vena cava saturation (SVCsat) as a marker for the adequacy of systemic oxygen delivery. The mean age was 6.7 months [standard deviation (SD), 8.6] and mean weight was 6.5 kg (SD, 2.2). Diagnoses were hypoplastic left heart syndrome (8), tricuspid or pulmonary atresia (10), and double-outlet right ventricle variants (2), all prior to cavo pulmonary anastomoses or complete repairs. Stepwise multiple regression analysis generated a model in which only NIRS was a significant independent predictor of SVCsat (p = 0.009). These results support the conclusion that NIRS can be a useful tool to evaluate awake single ventricle patients in the outpatient setting.

Original languageEnglish (US)
Pages (from-to)42-45
Number of pages4
JournalPediatric Cardiology
Issue number1
Publication statusPublished - Feb 2007



  • Near infrared spectroscopy
  • Single ventricle

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pediatrics, Perinatology, and Child Health

Cite this