TY - JOUR
T1 - Cerebrospinal fluid evaluation in neonates
T2 - Comparison of high-risk infants with and without meningitis
AU - Sarff, Larrie D.
AU - Platt, Lynn H.
AU - McCracken, George H.
PY - 1976/3
Y1 - 1976/3
N2 - Results of CSF examinations from 117 high-risk neonates were reviewed. The mean CSF cell count was 8.4 cells/mm3 and the range was 0 to 32 cells/mm3. Approximately 60% of the CSF WBC were polymorphonuclear leukocytes. Average CSF protein concentrations were 90 mg/dl (range, 20-170 mg/dl) in term and 115 mg/dl (range, 65-150 mg/dl) in preterm infants. The average CSF glucose was 81% of the blood glucose value in term and 74% in preterm infants. Comparison of these CSF findings with those from 119 infants with bacterial meningitis revealed that there was considerable overlapping of values, but only one of the 119 infants with meningitis had a completely normal initial CSF examination. The decision to initiate antimicrobial therapy in neonates with suspected meningitis must be based on total evaluation of the patient.
AB - Results of CSF examinations from 117 high-risk neonates were reviewed. The mean CSF cell count was 8.4 cells/mm3 and the range was 0 to 32 cells/mm3. Approximately 60% of the CSF WBC were polymorphonuclear leukocytes. Average CSF protein concentrations were 90 mg/dl (range, 20-170 mg/dl) in term and 115 mg/dl (range, 65-150 mg/dl) in preterm infants. The average CSF glucose was 81% of the blood glucose value in term and 74% in preterm infants. Comparison of these CSF findings with those from 119 infants with bacterial meningitis revealed that there was considerable overlapping of values, but only one of the 119 infants with meningitis had a completely normal initial CSF examination. The decision to initiate antimicrobial therapy in neonates with suspected meningitis must be based on total evaluation of the patient.
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U2 - 10.1016/S0022-3476(76)80271-5
DO - 10.1016/S0022-3476(76)80271-5
M3 - Article
C2 - 1245961
AN - SCOPUS:0017285310
SN - 0022-3476
VL - 88
SP - 473
EP - 477
JO - The Journal of pediatrics
JF - The Journal of pediatrics
IS - 3
ER -