Cerebrospinal fluid monoamine metabolites in alcoholic patients who attempt suicide

A. Roy, D. Lamparski, J. De Jong, B. Adinoff, B. Ravitz, D. T. George, D. Nutt, M. Linnoila

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Reduced cerebrospinal fluid (CSF) levels of the serotonin metabolite 5-hydroxyindoleacetic acid have been reported to be commonly associated with suicidal behaviour. Alcoholics are known to often manifest suicidal behaviour. Therefore, we compared cerebrospinal fluid levels of monoamine metabolites in alcoholics who had (n=20) and had not (n=108) attempted suicide and healthy volunteers (n=30). There were no significant differences among the 3 groups for CSF levels of either 5-hydroxyindoleacetic acid, the dopamine metabolite homovanillic acid, norepinephrine, or the norepinephrie metabolite 3-methoxy-4-hydroxyphenylglycol.

Original languageEnglish (US)
Pages (from-to)58-61
Number of pages4
JournalActa Psychiatrica Scandinavica
Volume81
Issue number1
StatePublished - 1990

Fingerprint

Alcoholics
Suicide
Cerebrospinal Fluid
Hydroxyindoleacetic Acid
Attempted Suicide
Homovanillic Acid
Dopamine
Serotonin
Norepinephrine
Healthy Volunteers

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuroscience(all)

Cite this

Roy, A., Lamparski, D., De Jong, J., Adinoff, B., Ravitz, B., George, D. T., ... Linnoila, M. (1990). Cerebrospinal fluid monoamine metabolites in alcoholic patients who attempt suicide. Acta Psychiatrica Scandinavica, 81(1), 58-61.

Cerebrospinal fluid monoamine metabolites in alcoholic patients who attempt suicide. / Roy, A.; Lamparski, D.; De Jong, J.; Adinoff, B.; Ravitz, B.; George, D. T.; Nutt, D.; Linnoila, M.

In: Acta Psychiatrica Scandinavica, Vol. 81, No. 1, 1990, p. 58-61.

Research output: Contribution to journalArticle

Roy, A, Lamparski, D, De Jong, J, Adinoff, B, Ravitz, B, George, DT, Nutt, D & Linnoila, M 1990, 'Cerebrospinal fluid monoamine metabolites in alcoholic patients who attempt suicide', Acta Psychiatrica Scandinavica, vol. 81, no. 1, pp. 58-61.
Roy, A. ; Lamparski, D. ; De Jong, J. ; Adinoff, B. ; Ravitz, B. ; George, D. T. ; Nutt, D. ; Linnoila, M. / Cerebrospinal fluid monoamine metabolites in alcoholic patients who attempt suicide. In: Acta Psychiatrica Scandinavica. 1990 ; Vol. 81, No. 1. pp. 58-61.
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