Changes in nerve conduction velocity after six weeks of glucoregulation with portable insulin infusion pumps

A. Pietri, A. L. Ehle, Philip Raskin

Research output: Contribution to journalArticle

113 Citations (Scopus)

Abstract

Near normal glucoregulation was maintained in 10 patients with insulin-dependent (type 1) diabetes mellitus for 6 wk with preprogrammed continuous subcutaneous insulin infusion using a portable battery-powered infusion pump (CSII). This form of therapy resulted in a statistically significant increase in motor nerve conduction velocity in the median and peroneal nerves compared with baseline values. There was no significant change in the motor nerve conduction studies. No changes occurred in five additional patients studied in similar fashion while on a conventional insulin regimen. These results suggest that the prevention of sustained hyperglycemia with SCII could theoretically result in the prevention of diabetic neuropathy. However, only long-term studies of CSII will provide the information necessary to determine the clinical relevance of the findings.

Original languageEnglish (US)
Pages (from-to)668-671
Number of pages4
JournalDiabetes
Volume29
Issue number8
StatePublished - 1980

Fingerprint

Infusion Pumps
Neural Conduction
Insulin
Subcutaneous Infusions
Peroneal Nerve
Diabetic Neuropathies
Median Nerve
Type 1 Diabetes Mellitus
Hyperglycemia
Therapeutics
Insulin-Dependent Diabetes Mellitus 6

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine

Cite this

Changes in nerve conduction velocity after six weeks of glucoregulation with portable insulin infusion pumps. / Pietri, A.; Ehle, A. L.; Raskin, Philip.

In: Diabetes, Vol. 29, No. 8, 1980, p. 668-671.

Research output: Contribution to journalArticle

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