Chapter 3 Signal transduction mechanisms in memory disorders

Sara C. Shalin, Regula Egli, Shari G. Birnbaum, Tania L. Roth, Jonathan M. Levenson, J. David Sweatt

Research output: Contribution to journalReview article

10 Scopus citations

Abstract

This chapter explores some of the molecular events contributing to memory formation and how, when these events malfunction, disturbances in memory occur. After a brief discussion of signaling in the hippocampus, we will explore the topics of human mental retardation syndromes that involve disruption of these processes, including Angelman syndrome (AS), Neurofibromatosis 1 (NF1)-associated learning disorders, Coffin-Lowry syndrome (CLS), Rubinstein-Taybi syndrome (RTS), and Rett syndrome (RTT).

Original languageEnglish (US)
Pages (from-to)25-41,384
JournalProgress in Brain Research
Volume157
DOIs
StatePublished - Jan 1 2006

Keywords

  • CBP
  • CaMKII
  • ERK
  • MAPK
  • MeCP2
  • NF1
  • RSK
  • epigenetics
  • learning
  • mental retardation

ASJC Scopus subject areas

  • Neuroscience(all)

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    Shalin, S. C., Egli, R., Birnbaum, S. G., Roth, T. L., Levenson, J. M., & Sweatt, J. D. (2006). Chapter 3 Signal transduction mechanisms in memory disorders. Progress in Brain Research, 157, 25-41,384. https://doi.org/10.1016/S0079-6123(06)57003-7