Chapter 3 Signal transduction mechanisms in memory disorders

Sara C. Shalin; Regula Egli; Shari G. Birnbaum; Tania L. Roth; Jonathan M. Levenson; J. David Sweatt

doi:10.1016/S0079-6123(06)57003-7

Chapter 3 Signal transduction mechanisms in memory disorders

Sara C. Shalin, Regula Egli, Shari G. Birnbaum, Tania L. Roth, Jonathan M. Levenson, J. David Sweatt

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

This chapter explores some of the molecular events contributing to memory formation and how, when these events malfunction, disturbances in memory occur. After a brief discussion of signaling in the hippocampus, we will explore the topics of human mental retardation syndromes that involve disruption of these processes, including Angelman syndrome (AS), Neurofibromatosis 1 (NF1)-associated learning disorders, Coffin-Lowry syndrome (CLS), Rubinstein-Taybi syndrome (RTS), and Rett syndrome (RTT).

Original language	English (US)
Pages (from-to)	25-41,384
Journal	Progress in Brain Research
Volume	157
DOIs	https://doi.org/10.1016/S0079-6123(06)57003-7
State	Published - 2006

Keywords

CBP
CaMKII
ERK
MAPK
MeCP2
NF1
RSK
epigenetics
learning
mental retardation

ASJC Scopus subject areas

General Neuroscience

Access to Document

10.1016/S0079-6123(06)57003-7

Cite this

@article{2ef381372f404009ab28e8cdf8ac4845,

title = "Chapter 3 Signal transduction mechanisms in memory disorders",

abstract = "This chapter explores some of the molecular events contributing to memory formation and how, when these events malfunction, disturbances in memory occur. After a brief discussion of signaling in the hippocampus, we will explore the topics of human mental retardation syndromes that involve disruption of these processes, including Angelman syndrome (AS), Neurofibromatosis 1 (NF1)-associated learning disorders, Coffin-Lowry syndrome (CLS), Rubinstein-Taybi syndrome (RTS), and Rett syndrome (RTT).",

keywords = "CBP, CaMKII, ERK, MAPK, MeCP2, NF1, RSK, epigenetics, learning, mental retardation",

author = "Shalin, {Sara C.} and Regula Egli and Birnbaum, {Shari G.} and Roth, {Tania L.} and Levenson, {Jonathan M.} and Sweatt, {J. David}",

year = "2006",

doi = "10.1016/S0079-6123(06)57003-7",

language = "English (US)",

volume = "157",

pages = "25--41,384",

journal = "Progress in Brain Research",

issn = "0079-6123",

publisher = "Elsevier",

}

TY - JOUR

T1 - Chapter 3 Signal transduction mechanisms in memory disorders

AU - Shalin, Sara C.

AU - Egli, Regula

AU - Birnbaum, Shari G.

AU - Roth, Tania L.

AU - Levenson, Jonathan M.

AU - Sweatt, J. David

PY - 2006

Y1 - 2006

N2 - This chapter explores some of the molecular events contributing to memory formation and how, when these events malfunction, disturbances in memory occur. After a brief discussion of signaling in the hippocampus, we will explore the topics of human mental retardation syndromes that involve disruption of these processes, including Angelman syndrome (AS), Neurofibromatosis 1 (NF1)-associated learning disorders, Coffin-Lowry syndrome (CLS), Rubinstein-Taybi syndrome (RTS), and Rett syndrome (RTT).

AB - This chapter explores some of the molecular events contributing to memory formation and how, when these events malfunction, disturbances in memory occur. After a brief discussion of signaling in the hippocampus, we will explore the topics of human mental retardation syndromes that involve disruption of these processes, including Angelman syndrome (AS), Neurofibromatosis 1 (NF1)-associated learning disorders, Coffin-Lowry syndrome (CLS), Rubinstein-Taybi syndrome (RTS), and Rett syndrome (RTT).

KW - CBP

KW - CaMKII

KW - ERK

KW - MAPK

KW - MeCP2

KW - NF1

KW - RSK

KW - epigenetics

KW - learning

KW - mental retardation

UR - http://www.scopus.com/inward/record.url?scp=33749626310&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33749626310&partnerID=8YFLogxK

U2 - 10.1016/S0079-6123(06)57003-7

DO - 10.1016/S0079-6123(06)57003-7

M3 - Review article

C2 - 17167902

AN - SCOPUS:33749626310

SN - 0079-6123

VL - 157

SP - 25-41,384

JO - Progress in Brain Research

JF - Progress in Brain Research

ER -

Chapter 3 Signal transduction mechanisms in memory disorders

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this