Characteristics of a novel treatment system for linear accelerator-based stereotactic radiosurgery

Ning Wen, Haisen Li, Kwang Song, Karen Chin-Snyder, Yujiao Qin, Jinkoo Kim, Maria Bellon, Misbah Gulam, Stephen Gardner, Anthony Doemer, Suneetha Devpura, James Gordon, Indrin Chetty, Farzan Siddiqui, Munther Ajlouni, Robert Pompa, Zane Hammoud, Michael Simoff, Steven Kalkanis, Benjamin Movsas & 1 others M. Salim Siddiqui

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The purpose of this study is to characterize the dosimetric properties and accuracy of a novel treatment platform (Edge radiosurgery system) for localizing and treating patients with frameless, image-guided stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Initial measurements of various components of the system, such as a comprehensive assessment of the dosimetric properties of the flattening filter-free (FFF) beams for both high definition (HD120) MLC and conical cone-based treatment, positioning accuracy and beam attenuation of a six degree of freedom (6DoF) couch, treatment head leakage test, and integrated end-to-end accuracy tests, have been performed. The end-to-end test of the system was performed by CT imaging a phantom and registering hidden targets on the treatment couch to determine the localization accuracy of the optical surface monitoring system (OSMS), cone-beam CT (CBCT), and MV imaging systems, as well as the radiation isocenter targeting accuracy. The deviations between the percent depth-dose curves acquired on the new linac-based system (Edge), and the previously published machine with FFF beams (TrueBeam) beyond Dmax were within 1.0% for both energies. The maximum deviation of output factors between the Edge and TrueBeam was 1.6%. The optimized dosimetric leaf gap values, which were fitted using Eclipse dose calculations and measurements based on representative spine radiosurgery plans, were 0.700 mm and 1.000 mm, respectively. For the conical cones, 6X FFF has sharper penumbra ranging from 1.2-1.8 mm (80%-20%) and 1.9-3.8 mm (90%-10%) relative to 10X FFF, which has 1.2-2.2mm and 2.3-5.1mm, respectively. The relative attenuation measurements of the couch for PA, PA (rails-in), oblique, oblique (rails-out), oblique (rails-in) were: -2.0%, -2.5%, -15.6%, -2.5%, -5.0% for 6X FFF and -1.4%, -1.5%, -12.2%, -2.5%, -5.0% for 10X FFF, respectively, with a slight decrease in attenuation versus field size. The systematic deviation between the OSMS and CBCT was -0.4 ± 0.2 mm, 0.1± 0.3mm, and 0.0 ± 0.1 mm in the vertical, longitudinal, and lateral directions. The mean values and standard deviations of the average deviation and maximum deviation of the daily Winston-Lutz tests over three months are 0.20 ± 0.03 mm and 0.66 ± 0.18 mm, respectively. Initial testing of this novel system demonstrates the technology to be highly accurate and suitable for frameless, linac-based SRS and SBRT treatment.

Original languageEnglish (US)
Pages (from-to)125-148
Number of pages24
JournalJournal of Applied Clinical Medical Physics
Volume16
Issue number4
StatePublished - 2015

Fingerprint

Particle Accelerators
Linear accelerators
Radiosurgery
flattening
linear accelerators
Cones
couches
deviation
Rails
filters
cones
Radiotherapy
rails
attenuation
Monitoring
radiation therapy
Therapeutics
Imaging Phantoms
Imaging systems
penumbras

Keywords

  • Commissioning
  • Conical cones
  • Edge
  • End-to-end testing
  • Six DoF couch

ASJC Scopus subject areas

  • Radiation
  • Instrumentation
  • Radiology Nuclear Medicine and imaging

Cite this

Wen, N., Li, H., Song, K., Chin-Snyder, K., Qin, Y., Kim, J., ... Salim Siddiqui, M. (2015). Characteristics of a novel treatment system for linear accelerator-based stereotactic radiosurgery. Journal of Applied Clinical Medical Physics, 16(4), 125-148.

Characteristics of a novel treatment system for linear accelerator-based stereotactic radiosurgery. / Wen, Ning; Li, Haisen; Song, Kwang; Chin-Snyder, Karen; Qin, Yujiao; Kim, Jinkoo; Bellon, Maria; Gulam, Misbah; Gardner, Stephen; Doemer, Anthony; Devpura, Suneetha; Gordon, James; Chetty, Indrin; Siddiqui, Farzan; Ajlouni, Munther; Pompa, Robert; Hammoud, Zane; Simoff, Michael; Kalkanis, Steven; Movsas, Benjamin; Salim Siddiqui, M.

In: Journal of Applied Clinical Medical Physics, Vol. 16, No. 4, 2015, p. 125-148.

Research output: Contribution to journalArticle

Wen, N, Li, H, Song, K, Chin-Snyder, K, Qin, Y, Kim, J, Bellon, M, Gulam, M, Gardner, S, Doemer, A, Devpura, S, Gordon, J, Chetty, I, Siddiqui, F, Ajlouni, M, Pompa, R, Hammoud, Z, Simoff, M, Kalkanis, S, Movsas, B & Salim Siddiqui, M 2015, 'Characteristics of a novel treatment system for linear accelerator-based stereotactic radiosurgery', Journal of Applied Clinical Medical Physics, vol. 16, no. 4, pp. 125-148.
Wen, Ning ; Li, Haisen ; Song, Kwang ; Chin-Snyder, Karen ; Qin, Yujiao ; Kim, Jinkoo ; Bellon, Maria ; Gulam, Misbah ; Gardner, Stephen ; Doemer, Anthony ; Devpura, Suneetha ; Gordon, James ; Chetty, Indrin ; Siddiqui, Farzan ; Ajlouni, Munther ; Pompa, Robert ; Hammoud, Zane ; Simoff, Michael ; Kalkanis, Steven ; Movsas, Benjamin ; Salim Siddiqui, M. / Characteristics of a novel treatment system for linear accelerator-based stereotactic radiosurgery. In: Journal of Applied Clinical Medical Physics. 2015 ; Vol. 16, No. 4. pp. 125-148.
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AU - Kim, Jinkoo

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AU - Gulam, Misbah

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