Characterization of a fibroma virus isolated from naturally occurring skin tumors in domestic rabbits

C. P. Raflo, R. G. Olsen, S. P. Pakes, W. S. Webster

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Abstract

Rabbit fibroma virus was isolated for the first time from skin tumors of New Zealand white rabbits from central Ohio. Electron microscopy demonstrated poxvirus particles in rabbit tumor cells. The etiologic agent was tentatively called Ohio isolate. Complement fixation tests and virus neutralization tests showed a close relationship between the Ohio isolate and other isolates of the rabbit fibroma virus. No serologic crossreaction was demonstrated between Ohio isolate and rabbit herpesvirus or the River's III herpesvirus. Heat inactivation studies and lipolytic sensitivity tests demonstrated the Ohio isolate to have properties similar to those reported for the fibroma myxoma group of poxviruses.

Original languageEnglish (US)
Title of host publicationLaboratory Animal Science
Pages525-532
Number of pages8
Volume23
Edition4
Publication statusPublished - 1973

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ASJC Scopus subject areas

  • Medicine(all)

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Raflo, C. P., Olsen, R. G., Pakes, S. P., & Webster, W. S. (1973). Characterization of a fibroma virus isolated from naturally occurring skin tumors in domestic rabbits. In Laboratory Animal Science (4 ed., Vol. 23, pp. 525-532)