Rabbit fibroma virus was isolated for the first time from skin tumors of New Zealand white rabbits from central Ohio. Electron microscopy demonstrated poxvirus particles in rabbit tumor cells. The etiologic agent was tentatively called Ohio isolate. Complement fixation tests and virus neutralization tests showed a close relationship between the Ohio isolate and other isolates of the rabbit fibroma virus. No serologic crossreaction was demonstrated between Ohio isolate and rabbit herpesvirus or the River's III herpesvirus. Heat inactivation studies and lipolytic sensitivity tests demonstrated the Ohio isolate to have properties similar to those reported for the fibroma myxoma group of poxviruses.
|Original language||English (US)|
|Title of host publication||Laboratory Animal Science|
|Number of pages||8|
|State||Published - 1973|
ASJC Scopus subject areas