Abstract
We cloned, sequenced, and mapped two divergent major histocompatibility class Ib genes from BALB/c mice. M9(d) and M10(d) both have the potential to encode full-length class I molecules, but transcripts were not readily detectable. M9 is 86% similar to M1 in its nucleotide sequence and maps next to it on YAC clones. M9 is only 64% similar to M10 and 60% to H2-K(k). Probes from M10 define a new subfamily of eight class I genes in C3H mice; five cluster directly distal to H2-T1, and three are located between M9-1-7-8 and M6-4-5 in the H2-M region.
Original language | English (US) |
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Pages (from-to) | 264-271 |
Number of pages | 8 |
Journal | Immunogenetics |
Volume | 47 |
Issue number | 3 |
DOIs | |
State | Published - 1998 |
Keywords
- Distal Mhc
- Divergent class Ib gene
- H2-M region
- M1 subfamily
- M10 subfamily
ASJC Scopus subject areas
- Immunology
- Genetics