TY - JOUR
T1 - Characterizing the right ventricle
T2 - Advancing our knowledge
AU - Chin, Kelly M.
AU - Coghlan, Gerry
N1 - Funding Information:
Publication of this supplement was supported by Actelion Pharmaceuticals Ltd.
Funding Information:
Gerry Coghlan, MD, is a member of the Speakers' Bureau of Actelion Pharmaceuticals, Ltd, GlaxoSmithKline, and Pfizer Inc; has worked as a consultant to Actelion Pharmaceuticals, Ltd, GlaxoSmithKline, and Pfizer Inc; has received research/grant support from Actelion Pharmaceuticals, Ltd; and employs a specialist nurse supported by GlaxoSmithKline.
PY - 2012/9/15
Y1 - 2012/9/15
N2 - Our ability to evaluate the right ventricle (RV) in pulmonary hypertension has traditionally been quite limited: the RV's complex anatomy is not adequately represented by 2-dimensional imaging, and our understanding of what is an adaptive and maladaptive RV response is incomplete. However, measures of RV function appear to be a strong predictor of survival in pulmonary hypertension. This is, therefore, a promising area for future study. To more fully understand the challenges and opportunities in this area, this article provides a review of RV embryology and anatomy, current assessment of the RV function, animal models of RV function, RVpulmonary artery coupling, and how translating lessons from studies of the left ventricle may increase our knowledge of the RV.
AB - Our ability to evaluate the right ventricle (RV) in pulmonary hypertension has traditionally been quite limited: the RV's complex anatomy is not adequately represented by 2-dimensional imaging, and our understanding of what is an adaptive and maladaptive RV response is incomplete. However, measures of RV function appear to be a strong predictor of survival in pulmonary hypertension. This is, therefore, a promising area for future study. To more fully understand the challenges and opportunities in this area, this article provides a review of RV embryology and anatomy, current assessment of the RV function, animal models of RV function, RVpulmonary artery coupling, and how translating lessons from studies of the left ventricle may increase our knowledge of the RV.
UR - http://www.scopus.com/inward/record.url?scp=84865500462&partnerID=8YFLogxK
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U2 - 10.1016/j.amjcard.2012.06.010
DO - 10.1016/j.amjcard.2012.06.010
M3 - Article
C2 - 22921029
AN - SCOPUS:84865500462
VL - 110
SP - S3-S8
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 6 SUPPL.
ER -