Chemotherapy Induces Cancer-Fighting B Cells

Zhida Liu; Yang Xin Fu

doi:10.1016/j.cell.2020.02.046

Chemotherapy Induces Cancer-Fighting B Cells

Zhida Liu, Yang Xin Fu

Research output: Contribution to journal › Comment/debate › peer-review

12 Scopus citations

Abstract

Tumor-infiltrating B cells are heterogeneous, and their roles in tumor immunity are controversial. In this issue of Cell, Lu and colleagues demonstrate that chemotherapy-induced complement signals promote the generation of ICOSL⁺B cells, which enhance tumor-specific T cell responses.

Original language	English (US)
Pages (from-to)	1037-1039
Number of pages	3
Journal	Cell
Volume	180
Issue number	6
DOIs	https://doi.org/10.1016/j.cell.2020.02.046
State	Published - Mar 19 2020

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2020.02.046

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@article{1356076ab2564da09735c25712aa7513,

title = "Chemotherapy Induces Cancer-Fighting B Cells",

abstract = "Tumor-infiltrating B cells are heterogeneous, and their roles in tumor immunity are controversial. In this issue of Cell, Lu and colleagues demonstrate that chemotherapy-induced complement signals promote the generation of ICOSL+B cells, which enhance tumor-specific T cell responses.",

author = "Zhida Liu and Fu, {Yang Xin}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = mar,

day = "19",

doi = "10.1016/j.cell.2020.02.046",

language = "English (US)",

volume = "180",

pages = "1037--1039",

journal = "Cell",

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T1 - Chemotherapy Induces Cancer-Fighting B Cells

AU - Liu, Zhida

AU - Fu, Yang Xin

PY - 2020/3/19

Y1 - 2020/3/19

N2 - Tumor-infiltrating B cells are heterogeneous, and their roles in tumor immunity are controversial. In this issue of Cell, Lu and colleagues demonstrate that chemotherapy-induced complement signals promote the generation of ICOSL+B cells, which enhance tumor-specific T cell responses.

AB - Tumor-infiltrating B cells are heterogeneous, and their roles in tumor immunity are controversial. In this issue of Cell, Lu and colleagues demonstrate that chemotherapy-induced complement signals promote the generation of ICOSL+B cells, which enhance tumor-specific T cell responses.

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U2 - 10.1016/j.cell.2020.02.046

DO - 10.1016/j.cell.2020.02.046

M3 - Comment/debate

C2 - 32142652

AN - SCOPUS:85081677502

SN - 0092-8674

VL - 180

SP - 1037

EP - 1039

JO - Cell

JF - Cell

IS - 6

ER -

Chemotherapy Induces Cancer-Fighting B Cells

Abstract

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