Chiral cyclopropanes: Asymmetric synthesis of constanolactones A and B

Jurong Yu, Jing Yu Lai, Jianhua Ye, Narayanan Balu, L. Manmohan Reddy, Wenhu Duan, Elaine R. Fogel, Jorge H. Capdevila, J R Falck

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

The title marine eicosanoids were prepared using a novel, stereoselective bis-annulation to create the characteristic cyclopropane-δ-lactone motif.

Original languageEnglish (US)
Pages (from-to)3939-3941
Number of pages3
JournalTetrahedron Letters
Volume43
Issue number21
DOIs
StatePublished - May 20 2002

Keywords

  • Annulation
  • Cyclopropanes
  • Eicosanoid
  • Natural products
  • Stereocontrol

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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    Yu, J., Lai, J. Y., Ye, J., Balu, N., Reddy, L. M., Duan, W., Fogel, E. R., Capdevila, J. H., & Falck, J. R. (2002). Chiral cyclopropanes: Asymmetric synthesis of constanolactones A and B. Tetrahedron Letters, 43(21), 3939-3941. https://doi.org/10.1016/S0040-4039(02)00699-8