Chloral hydrate toxicity in a term infant

M. A. Anyebuno, C. R. Rosenfeld

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Chlorate hydrate is commonly used for neonatal sedation, but blood levels are infrequently monitored, reflecting an underemphasis of acute toxic effects. This report describes a case of chloral hydrate toxicity in a term infant with cardiac, renal, neurologic, bladder and gastrointestinal dysfunction. The effects of exchange transfusion are described as well as pharmacokinetics.

Original languageEnglish (US)
Pages (from-to)116-120
Number of pages5
JournalDevelopmental Pharmacology and Therapeutics
Volume17
Issue number1-2
DOIs
StatePublished - Jan 1 1991

Keywords

  • Chloral hydrate
  • Ileus
  • Term infant
  • Trichloroethanol

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Pharmacology (medical)

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