Cholesterol - bile acid interactions in gallstone pathogenesis

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A technique for direct sampling of gallbladder and hepatic bile in humans provides strong support for the view that gallstones develop when bile becomes lithogenic, i.e., when the bile acid phospholipid to cholesterol ratio exceeds 10:1. Lithogenic bile may develop in normal persons through diurnal variation in bile lipid composition or result from excess secretion of biliary cholesterol and/or bile acid deficiency.

Original languageEnglish (US)
Pages (from-to)57-65
Number of pages9
JournalHospital Practice
Volume8
Issue number12
StatePublished - 1973

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Gallstones
Bile Acids and Salts
Bile
Cholesterol
Gallbladder
Phospholipids
Lipids
Liver

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cholesterol - bile acid interactions in gallstone pathogenesis. / Grundy, Scott M.

In: Hospital Practice, Vol. 8, No. 12, 1973, p. 57-65.

Research output: Contribution to journalArticle

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