Cholesterol: Factors Determining Blood Levels

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

High blood cholesterol is one of the leading risk factors for atherosclerosis. Blood cholesterol level is affected by a number of factors, including genetics, diet, tobacco use, level of physical activity, age, and menopause. Cholesterol is carried in the blood by macromolecular complexes called lipoproteins, which consist of a protein moiety (apolipoprotein) and also include, besides cholesterol, phospholipids, and triacylglycerol. A key determinant of cardiovascular risk is low-density lipoprotein (LDL) blood concentration. In turn, dietary fat quality and quantity is a major factor affecting LDL levels. Recent studies have shown that polyunsaturated fatty acids tend to reduce LDL cholesterol when replacing saturated fat in the diet.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Human Nutrition
PublisherElsevier Inc.
Pages335-340
Number of pages6
Volume1-4
ISBN (Electronic)9780123848857
ISBN (Print)9780123750839
DOIs
StatePublished - Jan 1 2012

Keywords

  • Atherosclerosis
  • Cholesterol
  • Coronary artery disease
  • Dietary fat
  • Polyunsaturated fatty acids
  • Saturated fat

ASJC Scopus subject areas

  • Medicine(all)

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