Choosing a bone healing model for evaluating bone graft substitutes

R. D. Welch, H. Zhang, D. G. Bronson, W. A. Pierce, D. J. Sucato

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The clinical indication for a particular bone graft substitute (BGS) material is an important guide for animal model selection. All BGSs are designed to replicate one or many of the attributes of autologous cortical or cancellous bone, to stimulate bone formation. It is observed that the rodent models are most suitable for addressing biocompatibility and degradation of BGS materials and the accessing the potential for osteogenesis. Knowledge of the bone healing parameters of the selected species and consideration of any special husbandry or anatomical issues will be need to insure the most appropriate selection is made.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - Dec 1 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress


OtherTransactions - 7th World Biomaterials Congress

ASJC Scopus subject areas

  • Engineering(all)


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