Chromosome 1 localization of the gene for CD34, a surface antigen of human stem cells

D. G. Tenen, A. B. Satterthwaite, R. Borson, D. Simmons, R. L. Eddy, T. B. Shows

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

CD34 is a surface anligen expressed on normal human hematopoietic stem cells, as well as on the blast cells of many patients with both lymphocytic and myelocytic leukemias. By Southern blot analysis of DN A from a panel of human x mouse somatic cell hybrids using a CD34 cDNA probe, we demonstrate that the gene for CD34 is located on human chromosome 1 in the lql2→qter region.

Original languageEnglish (US)
Pages (from-to)55-57
Number of pages3
JournalCytogenetic and Genome Research
Volume53
Issue number1
DOIs
StatePublished - 1990

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Chromosomes, Human, Pair 1
Surface Antigens
Stem Cells
Lymphoid Leukemia
Myeloid Leukemia
Hybrid Cells
Human Chromosomes
Hematopoietic Stem Cells
Southern Blotting
Genes
Complementary DNA

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Genetics(clinical)
  • Cell Biology

Cite this

Chromosome 1 localization of the gene for CD34, a surface antigen of human stem cells. / Tenen, D. G.; Satterthwaite, A. B.; Borson, R.; Simmons, D.; Eddy, R. L.; Shows, T. B.

In: Cytogenetic and Genome Research, Vol. 53, No. 1, 1990, p. 55-57.

Research output: Contribution to journalArticle

Tenen, D. G. ; Satterthwaite, A. B. ; Borson, R. ; Simmons, D. ; Eddy, R. L. ; Shows, T. B. / Chromosome 1 localization of the gene for CD34, a surface antigen of human stem cells. In: Cytogenetic and Genome Research. 1990 ; Vol. 53, No. 1. pp. 55-57.
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