Chromosome biology: Wapl spreads its wings

Hongtao Yu

Research output: Contribution to journalShort surveypeer-review

2 Scopus citations

Abstract

Chromosome segregation requires the removal of cohesion and catenation between sister chromosomes, two physical linkages established during DNA replication. Two new studies reveal that, among other functions, the wings apart-like protein (Wapl) coordinates cohesin removal with decatenation of sister chromosomes during mitosis in mammalian cells.

Original languageEnglish (US)
Pages (from-to)R923-R925
JournalCurrent Biology
Volume23
Issue number20
DOIs
StatePublished - Oct 21 2013

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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