Chronic sinusitis as a manifestation of primary immunodeficiency in adults

S. C. Manning, R. L. Wasserman, J. Leach, J. Truelson

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Twenty-three adult patients evaluated at a university medical center for severe refractory sinusitis were found to have a primary immunodeficiency on the basis of total immunoglobulin, IgG subclass, and vaccine response determinations. The most common finding was IgG3 deficiency with antibody hyporesponsiveness to pneumococcal vaccine. Treatment options included prophylactic antibiotics and aggressive management of associated allergies with intravenous immunoglobulin reserved for severely affected patients who failed more conservative therapy.

Original languageEnglish (US)
Pages (from-to)29-35
Number of pages7
JournalAmerican Journal of Rhinology
Volume8
Issue number1
StatePublished - 1994

Fingerprint

Sinusitis
Immunoglobulin G
Pneumococcal Vaccines
Intravenous Immunoglobulins
Immunoglobulins
Hypersensitivity
Vaccines
Anti-Bacterial Agents
Antibodies
Therapeutics
Conservative Treatment

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Chronic sinusitis as a manifestation of primary immunodeficiency in adults. / Manning, S. C.; Wasserman, R. L.; Leach, J.; Truelson, J.

In: American Journal of Rhinology, Vol. 8, No. 1, 1994, p. 29-35.

Research output: Contribution to journalArticle

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