Chronological Aging in African-American Skin: A Reliable Photonumeric Scale Demonstrates Age and Body Mass Index as Contributing Factors

Anna L. Chien, Ji Qi, Radhika Grandhi, Tamia Harris-Tryon, Noori Kim, Min Soo Jang, Omolara Olowoyeye, Diane Kuhn, Sherry Leung, Barbara M. Rainer, Flora Poon, Sabrina Sisto Alessi César, Jean Suh, Nancy Cheng, Ginette A. Okoye, Sewon Kang

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Increased photoprotection by natural melanin allows for African-Americans to be less impacted by photoaging than Caucasians. However, less is known about chronological aging in this population. Objective: To create a photonumeric scale for African-Americans to evaluate chronological skin aging and to explore contributing elements to intrinsic aging. Methods: Standardized photographs of the upper inner arm were taken from 75 African-American participants. Five participants were chosen as standards to create a 9-point photonumeric scale (0 = none, 8 = most severe). The scale was utilized by three blinded dermatologists to independently rate participants' photographs. Results: The interrater agreements were 0.768 (95% CI: 0.671-0.834) for trial 1 and 0.725 (0.608-0.794) for trial 2. The intrarater agreements were 0.757 (0.596-0.875), 0.850 (0.771-0.903), and 0.790 (0.686-0.855) for the three raters. Averaged chronological aging scores were correlated with participants' survey responses, which revealed age as a significant predictor (r = 0.72, p < 0.001). Limitation: Our study was limited by the sample size, although the number of study participants was similar on a investigation in Caucasians. Conclusion: This study created the first reliable photonumeric scale for chronologic skin aging in African-Americans and found increased age and greater BMI as contributors to intrinsic skin aging phenotype in this population.

Original languageEnglish (US)
JournalJournal of the National Medical Association
DOIs
StateAccepted/In press - Jan 1 2018

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Skin Aging
African Americans
Body Mass Index
Skin
Melanins
Sample Size
Population
Arm
Phenotype

Keywords

  • African Americans
  • Aging
  • Caucasians
  • Ethnic skin
  • Sun-exposed skin
  • Sun-protected skin

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Chronological Aging in African-American Skin : A Reliable Photonumeric Scale Demonstrates Age and Body Mass Index as Contributing Factors. / Chien, Anna L.; Qi, Ji; Grandhi, Radhika; Harris-Tryon, Tamia; Kim, Noori; Jang, Min Soo; Olowoyeye, Omolara; Kuhn, Diane; Leung, Sherry; Rainer, Barbara M.; Poon, Flora; César, Sabrina Sisto Alessi; Suh, Jean; Cheng, Nancy; Okoye, Ginette A.; Kang, Sewon.

In: Journal of the National Medical Association, 01.01.2018.

Research output: Contribution to journalArticle

Chien, AL, Qi, J, Grandhi, R, Harris-Tryon, T, Kim, N, Jang, MS, Olowoyeye, O, Kuhn, D, Leung, S, Rainer, BM, Poon, F, César, SSA, Suh, J, Cheng, N, Okoye, GA & Kang, S 2018, 'Chronological Aging in African-American Skin: A Reliable Photonumeric Scale Demonstrates Age and Body Mass Index as Contributing Factors', Journal of the National Medical Association. https://doi.org/10.1016/j.jnma.2018.01.005
Chien, Anna L. ; Qi, Ji ; Grandhi, Radhika ; Harris-Tryon, Tamia ; Kim, Noori ; Jang, Min Soo ; Olowoyeye, Omolara ; Kuhn, Diane ; Leung, Sherry ; Rainer, Barbara M. ; Poon, Flora ; César, Sabrina Sisto Alessi ; Suh, Jean ; Cheng, Nancy ; Okoye, Ginette A. ; Kang, Sewon. / Chronological Aging in African-American Skin : A Reliable Photonumeric Scale Demonstrates Age and Body Mass Index as Contributing Factors. In: Journal of the National Medical Association. 2018.
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abstract = "Background: Increased photoprotection by natural melanin allows for African-Americans to be less impacted by photoaging than Caucasians. However, less is known about chronological aging in this population. Objective: To create a photonumeric scale for African-Americans to evaluate chronological skin aging and to explore contributing elements to intrinsic aging. Methods: Standardized photographs of the upper inner arm were taken from 75 African-American participants. Five participants were chosen as standards to create a 9-point photonumeric scale (0 = none, 8 = most severe). The scale was utilized by three blinded dermatologists to independently rate participants' photographs. Results: The interrater agreements were 0.768 (95{\%} CI: 0.671-0.834) for trial 1 and 0.725 (0.608-0.794) for trial 2. The intrarater agreements were 0.757 (0.596-0.875), 0.850 (0.771-0.903), and 0.790 (0.686-0.855) for the three raters. Averaged chronological aging scores were correlated with participants' survey responses, which revealed age as a significant predictor (r = 0.72, p < 0.001). Limitation: Our study was limited by the sample size, although the number of study participants was similar on a investigation in Caucasians. Conclusion: This study created the first reliable photonumeric scale for chronologic skin aging in African-Americans and found increased age and greater BMI as contributors to intrinsic skin aging phenotype in this population.",
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T2 - A Reliable Photonumeric Scale Demonstrates Age and Body Mass Index as Contributing Factors

AU - Chien, Anna L.

AU - Qi, Ji

AU - Grandhi, Radhika

AU - Harris-Tryon, Tamia

AU - Kim, Noori

AU - Jang, Min Soo

AU - Olowoyeye, Omolara

AU - Kuhn, Diane

AU - Leung, Sherry

AU - Rainer, Barbara M.

AU - Poon, Flora

AU - César, Sabrina Sisto Alessi

AU - Suh, Jean

AU - Cheng, Nancy

AU - Okoye, Ginette A.

AU - Kang, Sewon

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Background: Increased photoprotection by natural melanin allows for African-Americans to be less impacted by photoaging than Caucasians. However, less is known about chronological aging in this population. Objective: To create a photonumeric scale for African-Americans to evaluate chronological skin aging and to explore contributing elements to intrinsic aging. Methods: Standardized photographs of the upper inner arm were taken from 75 African-American participants. Five participants were chosen as standards to create a 9-point photonumeric scale (0 = none, 8 = most severe). The scale was utilized by three blinded dermatologists to independently rate participants' photographs. Results: The interrater agreements were 0.768 (95% CI: 0.671-0.834) for trial 1 and 0.725 (0.608-0.794) for trial 2. The intrarater agreements were 0.757 (0.596-0.875), 0.850 (0.771-0.903), and 0.790 (0.686-0.855) for the three raters. Averaged chronological aging scores were correlated with participants' survey responses, which revealed age as a significant predictor (r = 0.72, p < 0.001). Limitation: Our study was limited by the sample size, although the number of study participants was similar on a investigation in Caucasians. Conclusion: This study created the first reliable photonumeric scale for chronologic skin aging in African-Americans and found increased age and greater BMI as contributors to intrinsic skin aging phenotype in this population.

AB - Background: Increased photoprotection by natural melanin allows for African-Americans to be less impacted by photoaging than Caucasians. However, less is known about chronological aging in this population. Objective: To create a photonumeric scale for African-Americans to evaluate chronological skin aging and to explore contributing elements to intrinsic aging. Methods: Standardized photographs of the upper inner arm were taken from 75 African-American participants. Five participants were chosen as standards to create a 9-point photonumeric scale (0 = none, 8 = most severe). The scale was utilized by three blinded dermatologists to independently rate participants' photographs. Results: The interrater agreements were 0.768 (95% CI: 0.671-0.834) for trial 1 and 0.725 (0.608-0.794) for trial 2. The intrarater agreements were 0.757 (0.596-0.875), 0.850 (0.771-0.903), and 0.790 (0.686-0.855) for the three raters. Averaged chronological aging scores were correlated with participants' survey responses, which revealed age as a significant predictor (r = 0.72, p < 0.001). Limitation: Our study was limited by the sample size, although the number of study participants was similar on a investigation in Caucasians. Conclusion: This study created the first reliable photonumeric scale for chronologic skin aging in African-Americans and found increased age and greater BMI as contributors to intrinsic skin aging phenotype in this population.

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