Circadian rhythms in infectious diseases and symbiosis

Filipa Rijo-Ferreira, Joseph S. Takahashi

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Timing is everything. Many organisms across the tree of life have evolved timekeeping mechanisms that regulate numerous of their cellular functions to optimize timing by anticipating changes in the environment. The specific environmental changes that are sensed depends on the organism. For animals, plants, and free-living microbes, environmental cues include light/dark cycles, daily temperature fluctuations, among others. In contrast, for a microbe that is never free-living, its rhythmic environment is its host's rhythmic biology. Here, we describe recent research on the interactions between hosts and microbes, from the perspective both of symbiosis as well as infections. In addition to describing the biology of the microbes, we focus specifically on how circadian clocks modulate these host-microbe interactions.

Original languageEnglish (US)
JournalSeminars in Cell and Developmental Biology
DOIs
StateAccepted/In press - 2021

Keywords

  • Bacteria
  • Circadian rhythms
  • Host
  • Infectious diseases
  • Parasite
  • Symbiosis
  • Virus

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

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