Circadian variation of sudden cardiac death or fatal myocardial infarction is abolished by propranolol in patients with heart disease and complex ventricular arrhythmias

Wilbert S. Aronow, Chul Ahn, Anthony D. Mercando, Stanley Epstein

Research output: Contribution to journalArticle

44 Scopus citations

Abstract

Sudden cardiac death and acute myocardial infarction have a circadian pattern with a significant morning peak.1-6 The circadian rhythm associated with acute myocardial infarction was not observed in patients receiving propranolol.6 We are reporting data on the times of sudden cardiac death or fatal myocardial infarction from a prospective study of patients ≥62 years of age with heart disease, complex ventricular arrhythmias, and a left ventricular ejection fraction ≥40% randomized to propranolol or no antiarrhythmic drug.7.

Original languageEnglish (US)
Pages (from-to)819-821
Number of pages3
JournalThe American journal of cardiology
Volume74
Issue number8
DOIs
StatePublished - Oct 15 1994

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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