Circuits controlling energy balance and mood: Inherently intertwined or just complicated intersections?

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16 Citations (Scopus)

Abstract

Recent reports of adverse psychiatric events from seemingly different types of weight loss therapies highlight a previously underestimated overlap between CNS circuits that control energy balance and those that regulate mood. In this Perspective, we discuss a few potential brain sites where the homeostatic and the hedonic pathways may intersect and suggest that a better understanding of both pathways is necessary for the development of more effective and safer antiobesity therapies.

Original languageEnglish (US)
Pages (from-to)902-909
Number of pages8
JournalCell Metabolism
Volume19
Issue number6
DOIs
StatePublished - Jun 3 2014

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Pleasure
Psychiatry
Weight Loss
Brain
Therapeutics

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology
  • Physiology

Cite this

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title = "Circuits controlling energy balance and mood: Inherently intertwined or just complicated intersections?",
abstract = "Recent reports of adverse psychiatric events from seemingly different types of weight loss therapies highlight a previously underestimated overlap between CNS circuits that control energy balance and those that regulate mood. In this Perspective, we discuss a few potential brain sites where the homeostatic and the hedonic pathways may intersect and suggest that a better understanding of both pathways is necessary for the development of more effective and safer antiobesity therapies.",
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