Clear cell odontogenic carcinoma: A diagnostic and therapeutic dilemma

Singh Avninder, Dinesh Rakheja, Amar Bhatnagar

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Background: Clear cell odontogenic carcinoma is a rare odontogenic tumor occurring in the anterior region of the mandible in 5th-7th decades and shows a female preponderance. It is potentially aggressive, capable of frequent recurrences and loco-regional and distant metastases. Case presentation: A 45-year-old woman presented with a radiolucent left mandibular swelling associated with loss of teeth. Left cervical lymph nodes were enlarged on palpation. The patient underwent resection of the tumor but consequent to resected margins being positive for tumor cells underwent left hemimandibulectomy with ipsilateral functional neck dissection and was free of recurrence at 8 months follow-up. Conclusion: Clear cell odontogenic carcinoma should be considered in the differential diagnosis of jaw tumors with conspicuous clear cell component. Curettage or conservative resection inevitably results in recurrences and/or metastasis and more radical resection is warranted in these tumors, especially when they are large and show soft tissue invasion.

Original languageEnglish (US)
Article number91
JournalWorld Journal of Surgical Oncology
Volume4
DOIs
StatePublished - Dec 12 2006

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Carcinoma
Recurrence
Neoplasms
Mandibular Osteotomy
Odontogenic Tumors
Neoplasm Metastasis
Tooth Loss
Neck Dissection
Curettage
Palpation
Cellular Structures
Therapeutics
Jaw
Mandible
Differential Diagnosis
Lymph Nodes

ASJC Scopus subject areas

  • Cancer Research
  • Surgery

Cite this

Clear cell odontogenic carcinoma : A diagnostic and therapeutic dilemma. / Avninder, Singh; Rakheja, Dinesh; Bhatnagar, Amar.

In: World Journal of Surgical Oncology, Vol. 4, 91, 12.12.2006.

Research output: Contribution to journalArticle

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