Clearing debris

Delong Meng, Jenna L Jewell

Research output: Contribution to journalComment/debate

Abstract

A new small molecule that targets the vacuolar H+-ATPase activates autophagy, inhibits mTORC1 signaling, and displays potential for clearing toxic protein aggregates involved in neurodegenerative diseases.

Original languageEnglish (US)
Pages (from-to)760-761
Number of pages2
JournalNature chemical biology
Volume15
Issue number8
DOIs
StatePublished - Aug 1 2019

Fingerprint

Vacuolar Proton-Translocating ATPases
Poisons
Autophagy
Neurodegenerative Diseases
mechanistic target of rapamycin complex 1
Protein Aggregates

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

Cite this

Clearing debris. / Meng, Delong; Jewell, Jenna L.

In: Nature chemical biology, Vol. 15, No. 8, 01.08.2019, p. 760-761.

Research output: Contribution to journalComment/debate

Meng, Delong ; Jewell, Jenna L. / Clearing debris. In: Nature chemical biology. 2019 ; Vol. 15, No. 8. pp. 760-761.
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