Clinical and echocardiographic diagnosis of patent ductus arteriosus in premature neonates

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The ductus arteriosus frequently fails to close in premature neonates. Considerable difference in opinion exists around what signifies a hemodynamically significant patent ductus arteriosus (PDA) and how reliable clinical signs are in determining the degree of the left-to-right shunting. Although reliance on clinical signs alone could delay the diagnosis of a PDA, there is insufficient evidence to suggest that early treatment improves outcome. Echocardiography is often used as the gold standard for diagnosing a PDA. A combination of echocardiographic measurements may assist in the early diagnosis of a PDA with a hemodynamically significant degree of left-to-right shunting, especially in extremely premature babies, where closure can be significantly delayed. Decision to treat PDA should be based on a combination of clinical signs and echocardiographic parameters. Monitoring B-type natriuretic peptide may be useful in the diagnosing neonates with symptomatic PDA.

Original languageEnglish (US)
Pages (from-to)147-149
Number of pages3
JournalEarly Human Development
Volume85
Issue number3
DOIs
StatePublished - Mar 2009

Fingerprint

Patent Ductus Arteriosus
Ductus Arteriosus
Brain Natriuretic Peptide
Echocardiography
Early Diagnosis

Keywords

  • Echocardiography
  • Indomethacin
  • Neonate
  • Patent ductus arteriosus
  • Premature

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Clinical and echocardiographic diagnosis of patent ductus arteriosus in premature neonates. / Chiruvolu, Arpitha; Punjwani, Poonam; Ramaciotti, Claudio.

In: Early Human Development, Vol. 85, No. 3, 03.2009, p. 147-149.

Research output: Contribution to journalArticle

@article{0586b2a36af541e39790d23ce95ec4df,
title = "Clinical and echocardiographic diagnosis of patent ductus arteriosus in premature neonates",
abstract = "The ductus arteriosus frequently fails to close in premature neonates. Considerable difference in opinion exists around what signifies a hemodynamically significant patent ductus arteriosus (PDA) and how reliable clinical signs are in determining the degree of the left-to-right shunting. Although reliance on clinical signs alone could delay the diagnosis of a PDA, there is insufficient evidence to suggest that early treatment improves outcome. Echocardiography is often used as the gold standard for diagnosing a PDA. A combination of echocardiographic measurements may assist in the early diagnosis of a PDA with a hemodynamically significant degree of left-to-right shunting, especially in extremely premature babies, where closure can be significantly delayed. Decision to treat PDA should be based on a combination of clinical signs and echocardiographic parameters. Monitoring B-type natriuretic peptide may be useful in the diagnosing neonates with symptomatic PDA.",
keywords = "Echocardiography, Indomethacin, Neonate, Patent ductus arteriosus, Premature",
author = "Arpitha Chiruvolu and Poonam Punjwani and Claudio Ramaciotti",
year = "2009",
month = "3",
doi = "10.1016/j.earlhumdev.2008.12.008",
language = "English (US)",
volume = "85",
pages = "147--149",
journal = "Early Human Development",
issn = "0378-3782",
publisher = "Elsevier Ireland Ltd",
number = "3",

}

TY - JOUR

T1 - Clinical and echocardiographic diagnosis of patent ductus arteriosus in premature neonates

AU - Chiruvolu, Arpitha

AU - Punjwani, Poonam

AU - Ramaciotti, Claudio

PY - 2009/3

Y1 - 2009/3

N2 - The ductus arteriosus frequently fails to close in premature neonates. Considerable difference in opinion exists around what signifies a hemodynamically significant patent ductus arteriosus (PDA) and how reliable clinical signs are in determining the degree of the left-to-right shunting. Although reliance on clinical signs alone could delay the diagnosis of a PDA, there is insufficient evidence to suggest that early treatment improves outcome. Echocardiography is often used as the gold standard for diagnosing a PDA. A combination of echocardiographic measurements may assist in the early diagnosis of a PDA with a hemodynamically significant degree of left-to-right shunting, especially in extremely premature babies, where closure can be significantly delayed. Decision to treat PDA should be based on a combination of clinical signs and echocardiographic parameters. Monitoring B-type natriuretic peptide may be useful in the diagnosing neonates with symptomatic PDA.

AB - The ductus arteriosus frequently fails to close in premature neonates. Considerable difference in opinion exists around what signifies a hemodynamically significant patent ductus arteriosus (PDA) and how reliable clinical signs are in determining the degree of the left-to-right shunting. Although reliance on clinical signs alone could delay the diagnosis of a PDA, there is insufficient evidence to suggest that early treatment improves outcome. Echocardiography is often used as the gold standard for diagnosing a PDA. A combination of echocardiographic measurements may assist in the early diagnosis of a PDA with a hemodynamically significant degree of left-to-right shunting, especially in extremely premature babies, where closure can be significantly delayed. Decision to treat PDA should be based on a combination of clinical signs and echocardiographic parameters. Monitoring B-type natriuretic peptide may be useful in the diagnosing neonates with symptomatic PDA.

KW - Echocardiography

KW - Indomethacin

KW - Neonate

KW - Patent ductus arteriosus

KW - Premature

UR - http://www.scopus.com/inward/record.url?scp=60849137193&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=60849137193&partnerID=8YFLogxK

U2 - 10.1016/j.earlhumdev.2008.12.008

DO - 10.1016/j.earlhumdev.2008.12.008

M3 - Article

C2 - 19217224

AN - SCOPUS:60849137193

VL - 85

SP - 147

EP - 149

JO - Early Human Development

JF - Early Human Development

SN - 0378-3782

IS - 3

ER -