Clinical and genetic evidence that juvenile arthritis is not a single disease

C. W. Fink, M. Fernandez-Vina, P. Stastny

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Ample evidence shows that what was formerly called 'juvenile rheumatoid arthritis' is not a single disease. At least six separate diseases were included as subgroups or subtypes of juvenile rheumatoid arthritis in other classifications. The clinical and laboratory features that differentiate these diseases are discussed. Genetic differences, primarily within the HLA system but also for T-cell receptor genes are described and correlated with the new clinical classification of arthritis.

Original languageEnglish (US)
Pages (from-to)1155-1169
Number of pages15
JournalPediatric clinics of North America
Volume42
Issue number5
DOIs
StatePublished - Jan 1 1995

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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